BackgroundA reliable biomarker signature for bipolar disorder sensitive to illness phase
would be of considerable clinical benefit. Among circulating blood-derived markers there …

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Depression is a major cause of morbidity and low quality of life among patients with
cardiovascular disease (CVD), and it is now considered as an independent risk factor for …

Introduction: Bipolar disorder (BD) is a chronic psychiatric disorder marked by clinical and
pathophysiological heterogeneity. There is a high expectation that personalized approaches …

ABSTRACT Introduction: Neurotrophin-3 (NT-3) is thought to play a role in the
neurobiological processes implicated in mood and anxiety disorders. NT-3 is a potential …

Background Schizophrenia is associated with patterns of aberrant neurobiological circuitry.
The disease complexity is mirrored by multiple biological interactions known to contribute to …

Neurotrophin is a growth factor that regulates the development and repair of the nervous
system. From all factors, two pioneer groups, the nerve growth factor (NGF) and brain …

Neurotrophins, a family of closely related proteins, were originally identified as growth
factors for survival, development, and function of neurons in both the central and peripheral …

Objective To date, the current diagnosis of major depressive disorder (MDD) still depends
on clinical symptomatologic criteria, misdiagnosis and ineffective treatment are common …

Neurotrophic factors, which can provide nutritional support to neurons and neuronal cells,
also played an important role in their proliferation and survival. As signaling molecules, it …