Advances in the genetic characterization of the malaria vector, Anopheles funestus, and implications for improved surveillance and control

JO Odero, IH Nambunga, DW Wangrawa, A Badolo… - Malaria Journal, 2023 - Springer
Anopheles mosquitoes present a major public health challenge in sub-Saharan Africa;
notably, as vectors of malaria that kill over half a million people annually. In parts of the east …

Malaria vector control in sub-Saharan Africa: complex trade-offs to combat the growing threat of insecticide resistance

RM Oxborough, KCF Chilito, F Tokponnon… - The Lancet Planetary …, 2024 - thelancet.com
Mass distribution of insecticide-treated nets (ITNs) has been a key factor in reducing malaria
cases and deaths in sub-Saharan Africa. A shortcoming has been the over-reliance on …

Effects of next-generation, dual-active-ingredient, long-lasting insecticidal net deployment on insecticide resistance in malaria vectors in Tanzania: an analysis of a 3 …

LA Messenger, NS Matowo, CL Cross… - The Lancet Planetary …, 2023 - thelancet.com
Background Insecticide resistance among malaria-vector species is a pervasive problem
that might jeopardise global disease-control efforts. Novel vector-control tools with different …

Genetic markers associated with the widespread insecticide resistance in malaria vector Anopheles funestus populations across Tanzania

JO Odero, IH Nambunga, JP Masalu, G Mkandawile… - Parasites & …, 2024 - Springer
Background Anopheles funestus is a leading vector of malaria in most parts of East and
Southern Africa, yet its ecology and responses to vector control remain poorly understood …

Phenotypic evidence of deltamethrin resistance and identification of selective sweeps in Anopheles mosquitoes on the Bijagós Archipelago, Guinea-Bissau

S Moss, RT Jones, E Pretorius, ET da Silva… - Scientific reports, 2024 - nature.com
Vector control in the Bijagós Archipelago of Guinea-Bissau currently relies on pyrethroid
insecticide-treated nets. However, data on insecticide resistance in Guinea-Bissau is limited …

Effectiveness of piperonyl butoxide and pyrethroid-treated long-lasting insecticidal nets (LLINs) versus pyrethroid-only LLINs with and without indoor residual spray …

N Protopopoff, JF Mosha, LA Messenger, E Lukole… - Malaria Journal, 2023 - Springer
Background After decades of success in reducing malaria through the scale-up of pyrethroid
long-lasting insecticidal nets (LLINs), the decline in the malaria burden has stalled …

[HTML][HTML] Widespread occurrence of copy number variants and fixation of pyrethroid target site resistance in Anopheles gambiae (sl) from southern Côte d'Ivoire

RMA Kouamé, A Lynd, JKI Kouamé, L Vavassori… - Current Research in …, 2023 - Elsevier
Resistance to pyrethroid and organophosphate insecticides in the malaria vector Anopheles
gambiae (sl) is conferred by a variety of genetic mutations, including single nucleotide …

[HTML][HTML] Is Anopheles gambiae (sensu stricto), the principal malaria vector in Africa prone to resistance development against new insecticides? Outcomes from …

S Azizi, NJ Mbewe, H Mo, F Edward, G Sumari… - Current Research in …, 2024 - Elsevier
Indiscriminate use of pesticides in the public health and agriculture sectors has contributed
to the development of resistance in malaria vectors following exposure to sub-lethal …

Genetic diversity of cytochrome P450s CYP6M2 and CYP6P4 associated with pyrethroid resistance in the major malaria vectors Anopheles coluzzii and Anopheles …

Y Fotso-Toguem, B Tene-Fossog, LMJ Mugenzi… - Genes, 2022 - mdpi.com
Assessing the genetic diversity of metabolic resistance genes, such as cytochrome P450s,
helps to understand the dynamics and evolution of resistance in the field. Here, we analyzed …

Resistance of Anopheles gambiae ss against commonly used insecticides and implication of cytochrome P450 monooxygenase in resistance to pyrethroids in …

ST Boussougou-Sambe, Y Djida… - BMC Infectious …, 2024 - Springer
Background Insecticides are a crucial component of vector control. However, resistance
constitute a threat on their efficacy and the gains obtained over the years through malaria …