Blood flow in the microcirculation

TW Secomb - Annual Review of Fluid Mechanics, 2017 - annualreviews.org
The microcirculation is an extensive network of microvessels that distributes blood flow
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …

Hydrodynamic mechanisms of cell and particle trapping in microfluidics

A Karimi, S Yazdi, AM Ardekani - Biomicrofluidics, 2013 - pubs.aip.org
Focusing and sorting cells and particles utilizing microfluidic phenomena have been
flourishing areas of development in recent years. These processes are largely beneficial in …

Multiscale modeling of blood flow: from single cells to blood rheology

DA Fedosov, H Noguchi, G Gompper - Biomechanics and modeling in …, 2014 - Springer
Mesoscale simulations of blood flow, where the red blood cells are described as deformable
closed shells with a membrane characterized by bending rigidity and stretching elasticity …

Why do red blood cells have asymmetric shapes even in a symmetric flow?

B Kaoui, G Biros, C Misbah - Physical review letters, 2009 - APS
Understanding why red blood cells (RBCs) move with an asymmetric shape (slipperlike
shape) in small blood vessels is a long-standing puzzle in blood circulatory research. By …

Theory and algorithms to compute Helfrich bending forces: a review

A Guckenberger, S Gekle - Journal of Physics: Condensed …, 2017 - iopscience.iop.org
Cell membranes are vital to shield a cell's interior from the environment. At the same time
they determine to a large extent the cell's mechanical resistance to external forces. In recent …

Manipulating nanoparticle transport within blood flow through external forces: An exemplar of mechanics in nanomedicine

H Ye, Z Shen, L Yu, M Wei, Y Li - Proceedings of the …, 2018 - royalsocietypublishing.org
A large number of nanoparticles (NPs) have been raised for diverse biomedical applications
and some of them have shown great potential in treatment and imaging of diseases. Design …

Phase-field modeling of the dynamics of multicomponent vesicles: Spinodal decomposition, coarsening, budding, and fission

JS Lowengrub, A Rätz, A Voigt - Physical Review E—Statistical, Nonlinear, and …, 2009 - APS
We develop a thermodynamically consistent phase-field model to simulate the dynamics of
multicomponent vesicles. The model accounts for bending stiffness, spontaneous curvature …

Noninertial lateral migration of vesicles in bounded Poiseuille flow

G Coupier, B Kaoui, T Podgorski, C Misbah - Physics of Fluids, 2008 - pubs.aip.org
Cross-streamline noninertial migration of a vesicle in a bounded Poiseuille flow is
investigated experimentally and numerically. The combined effects of the walls and of the …

Vesicles and red blood cells in flow: From individual dynamics to rheology

PM Vlahovska, T Podgorski… - Comptes …, 2009 - comptes-rendus.academie-sciences …
The rheology of suspensions of soft particles, such as red blood cells, is a long-standing
problem in science and engineering due to the complex interplay between deformable …

Hydrodynamic lift of vesicles and red blood cells in flow—from Fåhræus & Lindqvist to microfluidic cell sorting

TM Geislinger, T Franke - Advances in colloid and interface science, 2014 - Elsevier
Hydrodynamic lift forces acting on cells and particles in fluid flow receive ongoing attention
from medicine, mathematics, physics and engineering. The early findings of Fåhræus & …