Adverse events associated with childhood vaccines: evidence bearing on causality

RB Johnston Jr, CJ Howe, KR Stratton - 1993 - books.google.com
Childhood immunization is one of the major public health measures of the 20th century and
is now receiving special attention from the Clinton administration. At the same time, some …

Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance

T Martinov, BT Fife - Annals of the New York Academy of …, 2020 - Wiley Online Library
Abstract Type 1 diabetes (T1D) affects over a million Americans, and disease incidence is
on the rise. Despite decades of research, there is still no cure for this disease. Exciting beta …

HLA genetic discrepancy between latent autoimmune diabetes in adults and type 1 diabetes: LADA China Study No. 6

S Luo, J Lin, Z Xie, Y Xiang, P Zheng… - The Journal of …, 2016 - academic.oup.com
Context: The discrepancies in terms of human leukocyte antigen (HLA)-DRB1-DQA1-DQB1
conferred risks between latent autoimmune diabetes in adults (LADA) and type 1 diabetes …

Genetic predisposition and environmental factors leading to the development of insulin-dependent diabetes mellitus in Chilean children

F Perez-Bravo, E Carrasco, MD Gutierrez-Lopez… - Journal of Molecular …, 1996 - Springer
This study was designed to examine the hypothesis that some environmental factors
increase the risk for insulin-dependent diabetes mellitus. Data on dietary history was …

Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia

F Cucca, F Muntoni, R Lampis, F Frau, L Argiolas… - Human immunology, 1993 - Elsevier
The Sardinian population has an extremely high incidence of IDDM (30.2 of 100.000 in the
age group of 0–14 years). This study reports the molecular characterization of HLA class II …

Celiac disease in a Chilean population carrying Amerindian traits

M Araya, A Mondragón, F Pérez-Bravo… - Journal of pediatric …, 2000 - journals.lww.com
Background Although clinical manifestations of celiac disease may change throughout life,
clinical, histologic, immunologic, and genetic studies show that there are incomplete forms of …

Migrant populations and the incidence of Type 1 diabetes mellitus: an overview of the literature with a focus on the Spanish‐heritage countries in Latin America

M Serrano‐Rìos, A Goday… - … research and reviews, 1999 - Wiley Online Library
Type 1 diabetes mellitus (DM) is a 'chronic'autoimmune disorder leading to the destruction of
the pancreatic beta cell. The natural history of diabetes includes a long subclinical …

Progression to insulin-requiring diabetes in seronegative prediabetic subjects: the role of two HLA-DQ high-risk haplotypes

M Pietropaolo, DJ Becker, RE LaPorte, JS Dorman… - Diabetologia, 2002 - Springer
Aims/hypothesis: Most Caucasians with Type I (insulin-dependent) diabetes mellitus
develop an autoimmune form of diabetes known as Type IA diabetes, based on the …

Newborn HLA‐DR, DQ genotype screening: Age‐and ethnicity‐specific type 1 diabetes risk estimates

LM Emery, S Babu, TL Bugawan, JM Norris… - Pediatric …, 2005 - Wiley Online Library
Objective: Certain human leukocyte antigen (HLA)‐DR, DQ genotypes have been
associated with type 1 diabetes mellitus (T1DM) risk, although it is unknown whether the …

The next stage: molecular epidemiology

O Shpilberg, JS Dorman, RE Ferrell, M Trucco… - Journal of clinical …, 1997 - Elsevier
The traditional approach in epidemiology of relating exposure to an environmental agent
such as a drug or infective agent has been to measure an overall risk (ie, average and then …