Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program

MB Stein, DF Levey, Z Cheng, FR Wendt… - Nature …, 2021 - nature.com
We conducted genome-wide association analyses of over 250,000 participants of European
(EUR) and African (AFR) ancestry from the Million Veteran Program using electronic health …

[HTML][HTML] Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

[HTML][HTML] The role of the immune system in posttraumatic stress disorder

S Katrinli, NCS Oliveira, JC Felger… - Translational …, 2022 - nature.com
Posttraumatic stress disorder (PTSD) develops in a subset of individuals upon exposure to
traumatic stress. In addition to well-defined psychological and behavioral symptoms, some …

[图书][B] The psychology of religion: An empirical approach

RW Hood Jr, PC Hill, B Spilka - 2009 - books.google.com
Scholarly and comprehensive yet accessible, this state-of-the-science work is widely
regarded as the definitive graduate-level psychology of religion text. The authors synthesize …

[HTML][HTML] “GrimAge,” an epigenetic predictor of mortality, is accelerated in major depressive disorder

E Protsenko, R Yang, B Nier, V Reus… - Translational …, 2021 - nature.com
Major depressive disorder (MDD) is associated with premature mortality and is an
independent risk factor for a broad range of diseases, especially those associated with …

[HTML][HTML] Genome-wide DNA methylation association study of recent and cumulative marijuana use in middle aged adults

DR Nannini, Y Zheng, BT Joyce, K Kim, T Gao… - Molecular …, 2023 - nature.com
Marijuana is a widely used psychoactive substance in the US and medical and recreational
legalization has risen over the past decade. Despite the growing number of individuals …

Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and …

S Katrinli, AX Maihofer, AH Wani, JR Pfeiffer… - Molecular …, 2022 - nature.com
Epigenetic factors modify the effects of environmental factors on biological outcomes.
Identification of epigenetic changes that associate with PTSD is therefore a crucial step in …

[HTML][HTML] Cross-tissue correlations of genome-wide DNA methylation in Japanese live human brain and blood, saliva, and buccal epithelial tissues

S Nishitani, M Isozaki, A Yao, Y Higashino… - Translational …, 2023 - nature.com
Neuroepigenetics considers genetic sequences and the interplay with environmental
influences to elucidate vulnerability risk for various neurological and psychiatric disorders …