Trace amounts of copper in water induce β-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

DL Sparks, BG Schreurs - Proceedings of the National …, 2003 - National Acad Sciences
Despite the crucial role played by cholesterol and copper in nutrition and normal brain
function, recent evidence indicates that they may both be important factors in the etiology of …

Conditioning-specific reflex modification of the rabbit's nictitating membrane response and heart rate: behavioral rules, neural substrates, and potential applications to …

LB Burhans, C Smith-Bell, BG Schreurs - Behavioral Neuroscience, 2008 - psycnet.apa.org
Interest in classical conditioning is usually focused on anticipatory responses to a stimulus
associated with a significant event, and it is assumed that responses to the event itself are …

Emotion in motion: A three-stage model of aversive classical conditioning

DH Lindquist - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
An organism's ability to adapt to environmental challenges is aided by disparate neural
systems, acting independently and interactively to influence behavioral responding. With …

The effects of amygdala lesions on hippocampal activity and classical eyeblink conditioning in rats

MR Blankenship, R Huckfeldt, JJ Steinmetz… - Brain research, 2005 - Elsevier
The hippocampus and the amygdala have long been associated with memory, emotion, and
motivated behaviors. Although the role of these two brain areas in learning a simple …

Propranolol produces short-term facilitation of extinction in a rabbit model of post-traumatic stress disorder

LB Burhans, CA Smith-Bell, BG Schreurs - Neuropharmacology, 2018 - Elsevier
Post-traumatic stress disorder (PTSD) is a learning-based anxiety disorder with significant
public health challenges due to difficulties in treating the complex, multiple symptomology …

Amyloidogenesis induced by diet cholesterol and copper in a model mouse for Alzheimer's disease and protection effects of zinc and fluvastatin

D Yao, T Jing, L Niu, X Huang, Y Wang, X Deng… - Brain Research …, 2018 - Elsevier
Alzheimer's disease (AD) is one of the severe chronic diseases characterized with amyloid
beta (Aβ) aggregation and formation of senile-plaque (SP) like structures. Numerous risk …

Inactivation of the central nucleus of the amygdala abolishes conditioning-specific reflex modification of the rabbit (Oryctolagus cuniculus) nictitating membrane …

LB Burhans, BG Schreurs - Behavioral neuroscience, 2008 - psycnet.apa.org
The central nucleus (CE) of the amygdala has been gaining attention for its importance in
the plasticity underlying conditioned emotional responding. Already known for its role in …

Incubation of conditioning-specific reflex modification: implications for post traumatic stress disorder

BG Schreurs, CA Smith-Bell, LB Burhans - Journal of Psychiatric Research, 2011 - Elsevier
Incubation of fear has been used to account for the delayed manifestation of symptoms of
fear and anxiety including the delayed onset of Post Traumatic Stress Disorder (PTSD). We …

Dietary cholesterol impairs memory and memory increases brain cholesterol and sulfatide levels.

DS Darwish, D Wang, GW Konat… - Behavioral …, 2010 - psycnet.apa.org
Cholesterol and sulfatides play many important roles in learning and memory. To date, our
observations about the effects of cholesterol on learning have been assessed during …

Unpaired extinction: implications for treating post-traumatic stress disorder

BG Schreurs, CA Smith-Bell, LB Burhans - Journal of Psychiatric Research, 2011 - Elsevier
Extinction of fear is important for treating stress-related conditions particularly post-traumatic
stress disorder (PTSD). Although traditional extinction presents the feared stimulus by itself …