[HTML][HTML] Perioperative pain management and opioid stewardship: a practical guide

SJ Hyland, KK Brockhaus, WR Vincent, NZ Spence… - Healthcare, 2021 - mdpi.com
Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

Metabolism of psilocybin and psilocin: clinical and forensic toxicological relevance

RJ Dinis-Oliveira - Drug metabolism reviews, 2017 - Taylor & Francis
Psilocybin and psilocin are controlled substances in many countries. These are the two main
hallucinogenic compounds of the “magic mushrooms” and both act as agonists or partial …

[HTML][HTML] A review on tramadol toxicity: mechanism of action, clinical presentation, and treatment

S Nakhaee, C Hoyte, RC Dart, M Askari… - Forensic …, 2021 - Springer
Aims As an analgesic that acts upon the central nervous system (CNS), tramadol has gained
popularity in treating moderate to severe pain. Recently, it has been increasingly reported as …

[HTML][HTML] Pharmacokinetic and pharmacodynamic aspects of peyote and mescaline: clinical and forensic repercussions

RJ Dinis-Oliveira, CL Pereira… - Current molecular …, 2019 - ingentaconnect.com
Background: Mescaline (3, 4, 5-trimethoxyphenethylamine), mainly found in the Peyote
cactus (Lophophora williamsii), is one of the oldest known hallucinogenic agents that …

Pharmacokinetic and pharmacodynamic of bupropion: integrative overview of relevant clinical and forensic aspects

R Costa, NG Oliveira, RJ Dinis-Oliveira - Drug metabolism reviews, 2019 - Taylor & Francis
Bupropion is an atypical antidepressant of the aminoketone group, structurally related to
cathinone, associated with a wide interindividual variability. An extensive pharmacokinetic …

Comparative pharmacology and toxicology of tramadol and tapentadol

J Faria, J Barbosa, R Moreira, O Queirós… - … Journal of Pain, 2018 - Wiley Online Library
Moderate‐to‐severe pain represents a heavy burden in patients' quality of life, and
ultimately in the society and in healthcare costs. The aim of this review was to summarize …

[HTML][HTML] Tapentadol versus tramadol: a narrative and comparative review of their pharmacological, efficacy and safety profiles in adult patients

L Roulet, V Rollason, J Desmeules, V Piguet - Drugs, 2021 - Springer
We conducted a narrative review of the literature to compare the pharmacological, efficacy
and safety profiles of tapentadol and tramadol, and to assess the clinical interest of …

[HTML][HTML] Clinical pharmacology of tramadol and tapentadol, and their therapeutic efficacy in different models of acute and chronic pain in dogs and cats

A Domínguez-Oliva, A Casas-Alvarado… - Journal of Advanced …, 2021 - ncbi.nlm.nih.gov
Opioids are considered the gold standard to manage acute or chronic or mild to severe pain.
Tramadol is a widely prescribed analgesic drug for dogs and cats; it has a synthetic partial …

Codeine and opioid metabolism: implications and alternatives for pediatric pain management

V Chidambaran, S Sadhasivam… - Current Opinion in …, 2017 - journals.lww.com
Although routine preoperative genotyping to identify children at risk and personalized opioid
use for pediatric perioperative pain management is still a distant reality, current known …

[HTML][HTML] Pharmacological treatments and therapeutic drug monitoring in patients with chronic pain

F De Rosa, B Giannatiempo, B Charlier, A Coglianese… - Pharmaceutics, 2023 - mdpi.com
Pain is an unpleasant sensory and emotional experience that affects every aspect of a
patient's life and which may be treated through different pharmacological and non …