Since the discovery of the Kv1. 3 voltage-gated K+ channel in human T cells in 1984, ion
channels are considered crucial elements of the signal transduction machinery in the …

The human voltage gated potassium channel Kv1. 5 that conducts the IKur current is a key
determinant of the atrial action potential. Its mutations have been linked to hereditary forms …

Abstract Kalium (http://kaliumdb. org/) is a manually curated database that accumulates data
on potassium channel toxins purified from scorpion venom (KTx). This database is an open …

The Kv1. 3 channel has become a therapeutic target for the treatment of various diseases.
Several Kv1. 3 channel blockers have been characterized from scorpion venom; however …

The Colombian scorpion Centruroides margaritatus produces a venom considered of low
toxicity. Nevertheless, there are known cases of envenomation resulting in cardiovascular …

Six new peptides were isolated from the venom of the Mexican scorpion Centruroides
tecomanus; their primary structures were determined and the effects on ion channels were …

The scorpion Aegaeobuthus nigrocinctus inhabits areas in Turkey and the Levant region of
the Middle East where severe/lethal envenomings have been reported. Previous research …

Pain after envenomation is a well-known phenomenon: touching a nettle, stepping on a bee,
or becoming wrapped in jellyfish tentacles are relatively common encounters in our lives …

This work reports the isolation, chemical and functional characterization of two previously
unknown peptides purified from the venom of the scorpion Pandinus imperator …

Scorpion venoms are a rich source of bioactive molecules, but characterisation of toxin
peptides affecting cytosolic Ca2+, central to cell signalling and cell death, is limited. We …