Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

The development of single-cell multimodal assays provides a powerful tool for investigating
multiple dimensions of cellular heterogeneity, enabling new insights into development …

In the past decade, single-cell technologies have proliferated and improved from their
technically challenging beginnings to become common laboratory methods capable of …

Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …

The visualization and assessment of retinal microvasculature are important in the study,
diagnosis, monitoring, and guidance of treatment of ocular and systemic diseases. With the …

The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …

Since their inception, genome-wide association studies (GWAS) have identified more than a
hundred thousand single nucleotide polymorphism (SNP) loci that are associated with …

Convergent evidence associates exposure to endocrine disrupting chemicals (EDCs) with
major human diseases, even at regulation-compliant concentrations. This might be because …

Single-cell gene expression (transcriptomics) data are becoming robust and abundant, and
are increasingly used to track organisms along their life-course. This allows investigation …

Recent developments in immuno-oncology demonstrate that not only cancer cells, but also
the tumor microenvironment can guide precision medicine. A comprehensive and in-depth …