Neuropharmacological potential and delivery prospects of thymoquinone for neurological disorders

M Jakaria, DY Cho, M Ezazul Haque… - Oxidative medicine …, 2018 - Wiley Online Library
Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa and has various
pharmacological activities, such as protection against oxidative stress, inflammation, and …

Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of …

NA Omeiza, A Bakre, B Ben-Azu, AA Sowunmi… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Persistent ketamine insults to the central nervous system
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …

Morin attenuates neurochemical changes and increased oxidative/nitrergic stress in brains of mice exposed to ketamine: prevention and reversal of schizophrenia-like …

B Ben-Azu, AO Aderibigbe, AEO Eneni, AM Ajayi… - Neurochemical …, 2018 - Springer
Previous studies have revealed that morin (MOR), a neuroactive bioflavonoid, with proven
psychotropic and neuroprotective properties reduced schizophrenic-like behaviors in mice …

Role of the NRG1/ErbB4 and PI3K/AKT/mTOR signaling pathways in the anti-psychotic effects of aripiprazole and sertindole in ketamine-induced schizophrenia-like …

DA Nawwar, HF Zaki, RH Sayed - Inflammopharmacology, 2022 - Springer
Schizophrenia is a common mental disorder affecting patients' thoughts, behavior, and
cognition. Recently, the NRG1/ErbB4 signaling pathway emerged as a candidate …

Vinpocetine halts ketamine-induced schizophrenia-like deficits in rats: Impact on BDNF and GSK-3β/β-catenin pathway

HI Ahmed, SA Abdel-Sattar, HS Zaky - Naunyn-Schmiedeberg's archives …, 2018 - Springer
There are increasing evidences supporting the involvement of oxidative stress and
neuroinflammation in schizophrenia. Vinpocetine, a nootropic phosphodiesterase-1 …

Diosmin attenuates schizophrenia-like behavior, oxidative stress, and acetylcholinesterase activity in mice

AE Okubo Eneni, B Ben-Azu… - Drug metabolism and …, 2020 - degruyter.com
Objectives Diosmin (DSM), commonly isolated from various plants, is a citrus nutrient that
has been shown to increase intracellular antioxidant capacity and assuage symptoms …

Pretreatment with Carpolobia lutea ethanol extract prevents schizophrenia-like behavior in mice models of psychosis

NA Omeiza, AG Bakre, HA Abdulrahim, H Isibor… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Carpolobia lutea decoction is widely used as a
phytotherapeutic against central nervous system-related disorders including insomnia …

Ability of Indian pennywort Bacopa monnieri (L.) Pennell in the phytoremediation of sewage (greywater)

P Patnaik, SA Abbasi - Environmental Science and Pollution Research, 2020 - Springer
The freely and abundantly available amphibious plant Indian pennywort Bacopa monnieri
(L.) Pennell was able to phytoremediate sewage (greywater) quickly and substantially in …

[HTML][HTML] NMDA receptor modulation by Esculetin: Investigating behavioral, biochemical and neurochemical effects in schizophrenic mice model

I Khalid, U Saleem, B Ahmad, MF Hawwal… - Saudi Pharmaceutical …, 2024 - Elsevier
Schizophrenia, a global mental health disorder affecting approximately 1% of the
population, is characterized by neurotransmitter dysregulation, particularly dopamine …

Nano-hesperetin attenuates ketamine-induced schizophrenia-like symptoms in mice: participation of antioxidant parameters

AH Moghaddam, M Parhizgar, SK Jelodar, A Eslami… - …, 2023 - Springer
Rationale Antioxidant natural herb hesperetin (Hst) offers powerful medicinal properties.
Despite having noticeable antioxidant properties, it has limited absorption, which is a major …