Mechanisms of microtubule organization in differentiated animal cells

A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …

Microtubule organization is essential for maintaining cellular morphology and function

L Huang, Y Peng, X Tao, X Ding, R Li… - Oxidative medicine …, 2022 - Wiley Online Library
Microtubules (MTs) are highly dynamic polymers essential for a wide range of cellular
physiologies, such as acting as directional railways for intracellular transport and position …

Proximity labeling reveals non-centrosomal microtubule-organizing center components required for microtubule growth and localization

AD Sanchez, TC Branon, LE Cote, A Papagiannakis… - Current Biology, 2021 - cell.com
Microtubules are polarized intracellular polymers that play key roles in the cell, including in
transport, polarity, and cell division. Across eukaryotic cell types, microtubules adopt diverse …

[HTML][HTML] Sculpting the dendritic landscape: Actin, microtubules, and the art of arborization

VR Ouzounidis, B Prevo, DK Cheerambathur - Current Opinion in Cell …, 2023 - Elsevier
Dendrites are intricately designed neuronal compartments that play a vital role in the
gathering and processing of sensory or synaptic inputs. Their diverse and elaborate …

Persistent cell contacts enable E-cadherin/HMR-1-and PAR-3-based symmetry breaking within a developing C. elegans epithelium

VF Naturale, MA Pickett, JL Feldman - Developmental Cell, 2023 - cell.com
Tissue-wide patterning is essential to multicellular development, requiring cells to
individually generate polarity axes and coordinate them in space and time with neighbors …

Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons

S Shree, S Sutradhar, O Trottier, Y Tu, X Liang… - Science …, 2022 - science.org
The highly ramified arbors of neuronal dendrites provide the substrate for the high
connectivity and computational power of the brain. Altered dendritic morphology is …

Cellular cartography: Towards an atlas of the neuronal microtubule cytoskeleton

MK Iwanski, LC Kapitein - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Microtubules, one of the major components of the cytoskeleton, play a crucial role during
many aspects of neuronal development and function, such as neuronal polarization and …

Molecular mechanisms that mediate dendrite morphogenesis

JL Lefebvre - Current topics in developmental biology, 2021 - Elsevier
Neurons develop dendritic morphologies that bear cell type-specific features in dendritic
field size and geometry, branch placement and density, and the types and distributions of …

Microtubules originate asymmetrically at the somatic golgi and are guided via Kinesin2 to maintain polarity within neurons

A Mukherjee, PS Brooks, F Bernard, A Guichet… - Elife, 2020 - elifesciences.org
Neurons contain polarised microtubule arrays essential for neuronal function. How
microtubule nucleation and polarity are regulated within neurons remains unclear. We show …

With the permission of microtubules: an updated overview on microtubule function during axon pathfinding

C Sánchez-Huertas, E Herrera - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
During the establishment of neural circuitry axons often need to cover long distances to
reach remote targets. The stereotyped navigation of these axons defines the connectivity …