The pathology of small airways disease in COPD: historical aspects and future directions
A Higham, AM Quinn, JED Cançado, D Singh - Respiratory research, 2019 - Springer
Small airways disease (SAD) is a cardinal feature of chronic obstructive pulmonary disease
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
Airway-occluding mucus plugs and mortality in patients with chronic obstructive pulmonary disease
Importance Airway mucus plugs are common in patients with chronic obstructive pulmonary
disease (COPD); however, the association of airway mucus plugging and mortality in …
disease (COPD); however, the association of airway mucus plugging and mortality in …
Germinal centers determine the prognostic relevance of tertiary lymphoid structures and are impaired by corticosteroids in lung squamous cell carcinoma
K Siliņa, A Soltermann, FM Attar, R Casanova… - Cancer research, 2018 - AACR
In solid tumors, the presence of lymph node–like structures called tertiary lymphoid
structures (TLS) is associated with improved patient survival. However, little is known about …
structures (TLS) is associated with improved patient survival. However, little is known about …
[HTML][HTML] 2023 年GOLD 慢性阻塞性肺疾病诊断, 管理及预防全球策略更新要点解读
梁振宇， 王凤燕， 陈子正， 陈荣昌 - 中国全科医学, 2023 - chinagp.net
2023 年慢性阻塞性肺疾病全球倡议(GOLD) 维持了2022 年的基本框架,
但在慢性阻塞性肺疾病(以下简称慢阻肺) 定义, 评估, 初始治疗和随访期管理等方面进行了较大 …
但在慢性阻塞性肺疾病(以下简称慢阻肺) 定义, 评估, 初始治疗和随访期管理等方面进行了较大 …
Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease
Chronic obstructive lung disease is characterized by persistent abnormalities in epithelial
and immune cell function that are driven, at least in part, by infection. Analysis of …
and immune cell function that are driven, at least in part, by infection. Analysis of …
COPD immunopathology
G Caramori, P Casolari, A Barczyk, AL Durham… - Seminars in …, 2016 - Springer
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …
The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study
Background Chronic bronchitis (CB) in patients with COPD is associated with an
accelerated lung function decline and an increased risk of respiratory infections. Despite its …
accelerated lung function decline and an increased risk of respiratory infections. Despite its …
The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi
LLY Chan, DE Anderson, HS Cheng, FX Ivan… - Nature …, 2022 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and
infective exacerbations, however, in-vitro model systems for the study of host-pathogen …
infective exacerbations, however, in-vitro model systems for the study of host-pathogen …
Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects
Background Epidemiologic studies indicate that chronic cough and sputum production are
associated with increased mortality and disease progression in COPD subjects. Our …
associated with increased mortality and disease progression in COPD subjects. Our …
Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD
While the pharmacological management of chronic obstructive pulmonary disease (COPD)
has evolved from the drugs used to treat asthma, the treatment models are different and the …
has evolved from the drugs used to treat asthma, the treatment models are different and the …