Zebrafish as an emerging model for studying complex brain disorders

AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond

AV Kalueff, M Gebhardt, AM Stewart, JM Cachat… - Zebrafish, 2013 - liebertpub.com
Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …

Animal models of human disease: zebrafish swim into view

GJ Lieschke, PD Currie - Nature Reviews Genetics, 2007 - nature.com
Despite the pre-eminence of the mouse in modelling human disease, several aspects of
murine biology limit its routine use in large-scale genetic and therapeutic screening. Many …

Circuit neuroscience in zebrafish

RW Friedrich, GA Jacobson, P Zhu - Current Biology, 2010 - cell.com
A central goal of modern neuroscience is to obtain a mechanistic understanding of higher
brain functions under healthy and diseased conditions. Addressing this challenge requires …

Zebrafish models of autism spectrum disorder

DA Meshalkina, MN Kizlyk, EV Kysil, AD Collier… - Experimental …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by motor, social and cognitive deficits that develop early during childhood. The …

Fighting zebrafish: characterization of aggressive behavior and winner–loser effects

RF Oliveira, JF Silva, JM Simoes - Zebrafish, 2011 - liebertpub.com
Aggression is a key component of the behavioral repertoire of animals that impacts on their
Darwinian fitness. The available genetic tools in zebrafish make this species a promising …

Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments

DB Rosemberg, EP Rico, BHM Mussulini, ÂL Piato… - PloS one, 2011 - journals.plos.org
The open tank paradigm, also known as novel tank diving test, is a protocol used to evaluate
the zebrafish behavior. Several characteristics have been described for this species …

The endocannabinoid system in normal and pathological brain ageing

A Bilkei-Gorzo - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
The role of endocannabinoids as inhibitory retrograde transmitters is now widely known and
intensively studied. However, endocannabinoids also influence neuronal activity by exerting …

Zebrafish neurobehavioral phenomics for aquatic neuropharmacology and toxicology research

AV Kalueff, DJ Echevarria, S Homechaudhuri… - Aquatic Toxicology, 2016 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as an important model organism for aquatic
neuropharmacology and toxicology research. The behavioral/phenotypic complexity of …

Behaviour of telomere and telomerase during aging and regeneration in zebrafish

M Anchelin, L Murcia, F Alcaraz-Pérez… - PloS one, 2011 - journals.plos.org
Telomere length and telomerase activity are important factors in the pathobiology of human
diseases. Age-related diseases and premature aging syndromes are characterized by short …