A growing body of evidence suggests that the gut microbiota contributes to the development
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …

Emotion dysregulation (ED) describes a difficulty with the modulation of which emotions are
felt, as well as when and how these emotions are experienced or expressed. It is a focal …

Autism spectrum disorder (ASD) is one of the most common neurodevelopment disorders,
characterized by a multifactorial etiology based on the interaction of genetic and …

The gut-brain axis involves several bidirectional pathway communications including
microbiome, bacterial metabolites, neurotransmitters as well as immune system and is …

Neuroinflammation has been implicated in the pathogenesis of several neurologic and
psychiatric disorders. Microglia are key drivers of neuroinflammation and, in response to …

Schizophrenia is a complex and severe mental disorder that affects approximately 1% of the
global population. It is characterized by a wide range of symptoms, including delusions …

Background Anhedonia is a core symptom in patients with unipolar and bipolar depression.
However, sex-specific markers reflecting biological heterogeneity are lacking. Emerging …

Sex differences are pervasive in schizophrenia (SCZ), but the extent and magnitude of DNA
methylation (DNAm) changes underlying these differences remain uncharacterized. In this …

Background: Autism spectrum disorder (ASD) has seen a rise in prevalence, and the
immune system's role in brain development is increasingly recognized. This study …

Existing genetic studies of neuroticism have been largely limited to common variants. Here
we performed a large-scale exome analysis of white British individuals from UK Biobank …