Ascites, refractory ascites and hyponatremia in cirrhosis

B Fortune, A Cardenas - Gastroenterology Report, 2017 - academic.oup.com
Ascites is the most common complication related to cirrhosis and is associated with
increased morbidity and mortality. Ascites is a consequence of the loss of compensatory …

Translating our current understanding of ascites management into new therapies for patients with cirrhosis and fluid retention

E Pose, A Cardenas - Digestive Diseases, 2017 - karger.com
Ascites is the most common complication associated with cirrhosis resulting in poor quality
of life, high risk of development of other complications of cirrhosis, increased morbidity and …

[HTML][HTML] Chinese guidelines on the management of ascites and its related complications in cirrhosis

X Xu, Z Duan, H Ding, W Li, J Jia, L Wei, E Linghu… - Hepatology …, 2019 - Springer
Abstract The Chinese Society of Hepatology developed the current guidelines for the
Management of Ascites and Its Related Complications in Cirrhosis based on the published …

Tolvaptan response improves overall survival in patients with refractory ascites: a meta-analysis

I Bellos, K Kontzoglou, A Psyrri, V Pergialiotis - Digestive Diseases, 2020 - karger.com
Abstract Background and Aims: Refractory ascites represents a significant complication of
decompensated cirrhosis, associated with increased mortality rates. The aim of this meta …

Effectiveness and safety of tolvaptan in liver cirrhosis patients with edema: interim results of post‐marketing surveillance of tolvaptan in liver cirrhosis (START study)

I Sakaida, S Terai, M Kurosaki, M Yasuda… - Hepatology …, 2017 - Wiley Online Library
Aim Loop diuretics and spironolactone are used in patients with hepatic edema, but they are
sometimes associated with insufficient responses as well as adverse events. Tolvaptan, a …

Aquaporins and diseases pathogenesis: From trivial to undeniable involvements, a disease‐based point of view

M Ala, R Mohammad Jafari… - Journal of Cellular …, 2021 - Wiley Online Library
Aquaporins (AQPs), as transmembrane proteins, were primarily identified as water channels
with the ability of regulating the transmission of water, glycerol, urea, and other small‐sized …

Management of refractory cirrhotic ascites: challenges and solutions

H Fukui, H Kawaratani, K Kaji, H Takaya… - … evidence and research, 2018 - Taylor & Francis
Among the various risky complications of liver cirrhosis, refractory ascites is associated with
poor survival of cirrhotics and persistently worsens their quality of life (QOL). Major clinical …

[HTML][HTML] Tolvaptan treatment improves survival of cirrhotic patients with ascites and hyponatremia

S Wang, X Zhang, T Han, W Xie, Y Li, H Ma… - BMC …, 2018 - Springer
Background Although tolvaptan treatment improves hyponatremia, only few studies have
investigated whether tolvaptan actually benefits the survival of cirrhotic patients. This study …

Predictive parameter of tolvaptan effectiveness in cirrhotic ascites

H Kawaratani, H Fukui, K Moriya… - Hepatology …, 2017 - Wiley Online Library
Aims The efficacy of the vasopressin V2 receptor antagonist tolvaptan for difficult‐to‐treat
cirrhotic ascites has recently been reported. However, its effect is variable among patients …

Treatment for cirrhotic ascites

H Kawaratani, H Fukui, H Yoshiji - Hepatology Research, 2017 - Wiley Online Library
Common complications of decompensated liver cirrhosis are esophageal varices, hepatic
encephalopathy and ascites. After the onset of complications, the prognosis worsens. In …