Evolutionary mining and functional characterization of TnpB nucleases identify efficient miniature genome editors
G Xiang, Y Li, J Sun, Y Huo, S Cao, Y Cao, Y Guo… - Nature …, 2023 - nature.com
As the evolutionary ancestor of Cas12 nuclease, the transposon (IS200/IS605)-encoded
TnpB proteins act as compact RNA-guided DNA endonucleases. To explore their …
TnpB proteins act as compact RNA-guided DNA endonucleases. To explore their …
Transposon-encoded nucleases use guide RNAs to promote their selfish spread
Insertion sequences are compact and pervasive transposable elements found in bacteria,
which encode only the genes necessary for their mobilization and maintenance. IS200-and …
which encode only the genes necessary for their mobilization and maintenance. IS200-and …
Marine viral particles reveal an expansive repertoire of phage-parasitizing mobile elements
Phage satellites are mobile genetic elements that propagate by parasitizing bacteriophage
replication. We report here the discovery of abundant and diverse phage satellites that were …
replication. We report here the discovery of abundant and diverse phage satellites that were …
[HTML][HTML] Self-empowerment of life through RNA networks, cells and viruses
L Villarreal, G Witzany - F1000Research, 2023 - ncbi.nlm.nih.gov
Our understanding of the key players in evolution and of the development of all organisms in
all domains of life has been aided by current knowledge about RNA stem-loop groups, their …
all domains of life has been aided by current knowledge about RNA stem-loop groups, their …
[HTML][HTML] Unity among the diverse RNA-guided CRISPR-Cas interference mechanisms
CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-
associated) systems are adaptive immune systems that protect bacteria and archaea from …
associated) systems are adaptive immune systems that protect bacteria and archaea from …
Transformation of hydroxylated polychlorinated biphenyls by bacterial 2-hydroxybiphenyl 3-monooxygenase
J Suman, K Sredlova, S Fraraccio, M Jerabkova… - Chemosphere, 2024 - Elsevier
Abstract Monohydroxylated PCBs (OH-PCBs) are an (eco) toxicologically significant group
of compounds, as they arise from the oxidation of polychlorinated biphenyls (PCBs) and, at …
of compounds, as they arise from the oxidation of polychlorinated biphenyls (PCBs) and, at …
[HTML][HTML] Interaction between indigenous hydrocarbon-degrading bacteria in reconstituted mixtures for remediation of weathered oil in soil
N Al-Kaabi, Z Al Disi, MA Al-Ghouti, TI Solling… - Biotechnology …, 2022 - Elsevier
It has been demonstrated that biostimulation is necessary to investigate the interactions
between indigenous bacteria and establish an approach for the bioremediation of soils …
between indigenous bacteria and establish an approach for the bioremediation of soils …
[HTML][HTML] Transposon-encoded nucleases use guide RNAs to selfishly bias their inheritance
Insertion sequences (IS) are compact and pervasive transposable elements found in
bacteria, which encode only the genes necessary for their mobilization and maintenance …
bacteria, which encode only the genes necessary for their mobilization and maintenance …
Going viral: The role of mobile genetic elements in bacterial immunity
Bacteriophages and other mobile genetic elements (MGEs) pose a significant threat to
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …
Search for origins of anti-CRISPR proteins by structure comparison
Many bacterial and archaeal viruses encode anti-CRISPR proteins (Acrs) that specifically
inhibit CRISPR-Cas systems via various mechanisms. The majority of the Acrs are small …
inhibit CRISPR-Cas systems via various mechanisms. The majority of the Acrs are small …