Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies

H Turkez, ME Arslan, A Tatar, A Mardinoglu - Neurochemistry international, 2021 - Elsevier
Glioblastoma (GB) is the most common and aggressive primary malignant astrocytoma
correlated with poor patient survival. There are no curative treatments for GB, and it …

The dual role of boron in vitro neurotoxication of glioblastoma cells via SEMA3F/NRP2 and ferroptosis signaling pathways

F Kar, C Hacioğlu, S Kaçar - Environmental Toxicology, 2023 - Wiley Online Library
Glioblastoma multiform (GBM) is a malignant tumor cancer that originates from the star‐
shaped glial support tissues, namely astrocytes, and it is associated with a poor prognosis in …

Borax regulates iron chaperone‐and autophagy‐mediated ferroptosis pathway in glioblastoma cells

C Hacioglu, F Kar, F Davran… - Environmental …, 2023 - Wiley Online Library
Glioblastoma (GBM) is classified as a stage‐IV glioma. Unfortunately, there are currently no
curative treatments for GBM. Poly (rC)‐binding protein 1 (PCBP1) is a cytosolic iron …

Boron Compounds Mitigate 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity in Human Peripheral Blood Mononuclear Cells

ME Arslan, C Baba, OO Tozlu - Toxics, 2024 - mdpi.com
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) stands as one of the most potent halogenated
polycyclic hydrocarbons, known to inflict substantial cytotoxic effects on both animal and …

Therapeutic effects of newly synthesized boron compounds (BGM and BGD) on hepatocellular carcinoma

MK Gündüz, M Bolat, G Kaymak, D Berikten… - … Trace Element Research, 2022 - Springer
Boron has an important potential for facilitating biological activity and for use in
pharmaceutical drug design. Boron glycine monoester (BGM) and boron glycine diester …

Calotropis procera: A double edged sword against glioblastoma, inhibiting glioblastoma cell line growth by targeting histone deacetylases (HDAC) and angiogenesis

SHS Alanazi, MF Khan, AM Alazami, A Baabbad… - Heliyon, 2024 - cell.com
Despite substantial investments in anti-glioblastoma (GBM) drug discovery over the last
decade, progress is limited to preclinical stages, with clinical studies frequently encountering …

Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds

SB Oguzkan, H Turkez, HI Ugras, A Tatar… - Inorganics, 2023 - mdpi.com
In this study, the biological properties of novel borenium and borinium compounds in terms
of their oxidative, genotoxic, and cytotoxic effects were assessed on cultured human …

Boric acid treatment strengthens the cytotoxic effect of sorafenib on triple negative breast cancer cell lines

E Kahraman, E Göker - Celal Bayar University Journal of Science, 2023 - dergipark.org.tr
In recent years, it has been demonstrated that combinational therapies have shown
promising results in the treatment of triple negative breast cancer. However, the effect of the …

Antimicrobial chitosan-sodium tetrafluoroborate (NaBF4) hydrogels for topical applications

Z İyigündoğdu - Journal of Boron, 2023 - dergipark.org.tr
Infection of a wound is one of the most important reasons delaying the recovery of an injured
tissue. In this study, chitosan-based hydrogels were loaded with different concentrations of …

[HTML][HTML] Synthesis of new boron derived compounds; anticancer, antioxidant and antimicrobial effect in vitro glioblastoma tumor model

M Koldemir-Gündüz, HE Aydin… - Journal of Korean …, 2021 - synapse.koreamed.org
Objective The aim of our study is to investigate the cytotoxic, antioxidant, and antimicrobial
effects of newly synthesized boron compounds in U87MG glioblastoma cell treatment …