Camellia sinensis (tea), one of the most popular commercial crops, is commonly applied in
all parts of the world. The main active ingredients of tea include polyphenols, alkaloids …

Purpose We intend to assess the effect of the conditioned medium of Caffeine pulsed MSCS
in the amelioration of rheumatoid arthritis (RA)-afflicted rats. Methods MSCs were incubated …

Purinergic signaling has been implicated in many biological functions, including
development. In this study, we investigate the functions of extracellular adenosine and …

Osteoporosis is a metabolic disease that affects bone tissue and is highly associated with
bone fractures. Typical osteoporosis fracture treatments, such as bisphosphonates and …

Background: Although caffeine generally offers benefits to human health, its impact on bone
metabolism remains unclear. Aim and Methods: This study aimed to systematically evaluate …

Osteoporosis is a metabolic disease that affects bone tissue and is highly associated with
bone fractures. Due to the low bioavailability of conventional treatments for this disease, an …

Abstract Kisspeptin (Kp-10) is a neuropeptide that binds to GPR54 receptors, exerting
several functions mainly in the nervous and reproductive systems of the body. However, its …

This study explores the impact of chronic caffeine intake on collagen deposition in long
bones and correlates it with morphometric and metabolic alterations in Wistar rats. Animals …

Aims Although excessive fat and caffeine intake are independent risk factors for bone
microstructural and functional disturbances, their association remains overlooked. Thus, we …

RAW 264.7 cells and HUVECs were compared to evaluate the effects of dialyzed coffee
extract (DCE) and artificial coffee (AC). Immunoprecipitation high performance liquid …