The control of apoptosis in mammals has been historically associated with the activity of the
BCL-2 family of proteins at the mitochondria. In the past years, a novel group of cell death …

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis and
limited treatment options. Efforts to identify effective treatments are thwarted by limited …

The development of new drugs able to directly activate the apoptotic machinery in tumors is
a promising approach in the treatment of cancer as it is independent of sensors and …

Autophagy is a self-degradative process involved both in basal turnover of cellular
components and in response to nutrient starvation or organelle damage in a wide range of …

Creatine monohydrate (CrM) supplementation has been shown to increase fat-free mass
and muscle power output possibly via cell swelling. Little is known about the cellular …

Programmed cell death (PCD) plays important roles in the development and physiology of
both animals and plants, but it is unclear whether similar mechanisms are employed. Bax …

Background Alzheimer's disease (AD) is characterized by a neurodegenerative progression
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …

There is evidence that the obesity phenotype in the Caucasian populations is associated
with variations in several genes, including neuronal growth regulator 1 (NEGR1), SEC16 …

There is growing evidence that long non-coding RNAs (lncRNAs) are related to cancer
development. In the present study, we found that the expression levels of lncRNA-SNHG7 …

We have investigated the expression and function of a novel protein encoded by open
reading frame (ORF) K7 of Kaposi's sarcoma‐associated herpesvirus (KSHV) …