Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

Existing anticancer therapeutic modalities in clinical settings lack efficacy and fail to
completely cure cancers. Clearly understandable and mechanistic approaches are …

Small cell lung cancer (SCLC) is a neuroendocrine tumor with a high degree of malignancy.
Due to limited treatment options, patients with SCLC have a poor prognosis. We have found …

Objective. A systematic review of dosimetry in Targeted Alpha Therapy (TAT) has been
performed, identifying the common issues. Approach. The systematic review was performed …

The development of diagnostic and therapeutic radiopharmaceuticals is an hot topic in
nuclear medicine. Several radiolabeled antibodies are under development necessitating …

Purpose In treating prostate cancer, distinguishing alpha and beta therapies is vital for
efficient radiopharmaceutical delivery. Our study introduces a 3D image-based …

Purpose In the current work, the RBE of a 212Pb-conjugated anti-HER2/neu antibody
construct has been evaluated, in vitro, by colony formation assay. The RBE was estimated …

Angiogenesis is a key step in the initiation and progression of an invasive breast cancer.
High microvessel density by morphological characterization predicts metastasis and poor …

Targeted radionuclide therapy (TRT) is based on injections of cancer-specific molecules
conjugated with radioactive nuclides. Despite the specificity of this treatment, it is not devoid …

An emerging safe and efficient targeted method of treating many different types of cancer is
radiopharmaceutical treatment (RPT). RPT uses medications that either bind more …