Techniques for phosphopeptide enrichment prior to analysis by mass spectrometry
JD Dunn, GE Reid, ML Bruening - Mass spectrometry reviews, 2010 - Wiley Online Library
Mass spectrometry is the tool of choice to investigate protein phosphorylation, which plays a
vital role in cell regulation and diseases such as cancer. However, low abundances of …
vital role in cell regulation and diseases such as cancer. However, low abundances of …
Phosphopeptide enrichment using metal oxide affinity chromatography
A Leitner - TrAC Trends in Analytical Chemistry, 2010 - Elsevier
The demand for effective sample preparation strategies that enable the in-depth study of
protein phosphorylation has spawned a number of selective affinity techniques that allow …
protein phosphorylation has spawned a number of selective affinity techniques that allow …
Recent advances in phosphopeptide enrichment: strategies and techniques
Phosphoproteomics has become one of the most active research areas in proteomics
studies. Phosphopeptide enrichment is a critical and indispensable step in …
studies. Phosphopeptide enrichment is a critical and indispensable step in …
Ordered mesoporous alumina with ultra-large pores as an efficient absorbent for selective bioenrichment
Alumina has recently turned out to be effective in enrichment of biomacrolecules like
phosphopeptides due to its good affinity to phosphor groups. Ordered mesoporous alumina …
phosphopeptides due to its good affinity to phosphor groups. Ordered mesoporous alumina …
Metal oxides in sample pretreatment
Sample pretreatment is a fundamental and essential step in almost all analytical procedures,
especially for the analysis of biological and environmental samples with complex matrix. In …
especially for the analysis of biological and environmental samples with complex matrix. In …
Enrichment of phosphorylated peptides with metal–organic framework nanosheets for serum profiling of diabetes and phosphoproteomics analysis
SS Yang, YJ Chang, H Zhang, X Yu, W Shang… - Analytical …, 2018 - ACS Publications
Capturing phosphopeptides from complicated biological samples is essential for the
discovery of new post-translational modification sites and disease diagnostics. Although …
discovery of new post-translational modification sites and disease diagnostics. Although …
Development of phosphopeptide enrichment techniques for phosphoproteome analysis
Protein phosphorylation is one of the most biologically relevant and ubiquitous post-
translational modifications. The analysis of protein phosphorylation is very challenging due …
translational modifications. The analysis of protein phosphorylation is very challenging due …
A poly (ethylene glycol)-brush decorated magnetic polymer for highly specific enrichment of phosphopeptides
L Zhao, H Qin, Z Hu, Y Zhang, H Zou - Chemical Science, 2012 - pubs.rsc.org
Immobilized metal affinity chromatography (IMAC) is a powerful method in phosphopeptide
enrichment. However, the achievement of highly specific enrichment and sensitive detection …
enrichment. However, the achievement of highly specific enrichment and sensitive detection …
On‐plate‐selective enrichment of glycopeptides using boronic acid‐modified gold nanoparticles for direct MALDI‐QIT‐TOF MS analysis
In this study, an on‐plate‐selective enrichment method is developed for fast and efficient
glycopeptide investigation. Gold nanoparticles were first spotted and sintered on a stainless …
glycopeptide investigation. Gold nanoparticles were first spotted and sintered on a stainless …
Coupling strong anion-exchange monolithic capillary with MALDI-TOF MS for sensitive detection of phosphopeptides in protein digest
Protein phosphorylation is one of the most biologically relevant and ubiquitous post-
translational modifications. Matrix-assisted laser desorption ionization time-of-flight mass …
translational modifications. Matrix-assisted laser desorption ionization time-of-flight mass …