Prevalence, risk, and challenges of extemporaneous preparation for pediatric patients in developing nations: A review
Extemporaneous preparations are still widely prescribed for pediatric patients with special
treatments of certain doses and/or combinations of drugs. Several problems related to …
treatments of certain doses and/or combinations of drugs. Several problems related to …
Extent, reasons and consequences of off-labeled and unlicensed drug prescription in hospitalized children: a narrative review
W Shuib, XY Wu, F Xiao - World Journal of Pediatrics, 2021 - Springer
Background Off-label and unlicensed prescriptions pose a severe safety concern among the
pediatric population. We aimed to summarize the up-to-date evidence on the extent …
pediatric population. We aimed to summarize the up-to-date evidence on the extent …
Design, evaluation and comparison of nanostructured lipid carriers and chitosan nanoparticles as carriers of poorly soluble drugs to develop oral liquid formulations …
There is a serious need of pediatric drug formulations, whose lack causes the frequent use
of extemporaneous preparations obtained from adult dosage forms, with consequent safety …
of extemporaneous preparations obtained from adult dosage forms, with consequent safety …
Management guideline for the off-label use of medicine in China (2021)
W Zuo, Y Sun, R Liu, L Du, N Yang, W Sun… - Expert review of …, 2022 - Taylor & Francis
Background Off-label drug use embodies a thorough clinical diagnosis and evaluation of
treatment needs and should not be confused with unreasonable drug use, but it also faces …
treatment needs and should not be confused with unreasonable drug use, but it also faces …
Evaluation of the safety of using propofol for paediatric procedural sedation: a systematic review and meta-analysis
S Kim, S Hahn, M Jang, Y Choi, H Hong, JH Lee… - Scientific Reports, 2019 - nature.com
Propofol is one of the most widely used drugs for paediatric procedural sedation owing to its
known advantages, but some concerns remain regarding respiratory and/or cardiac …
known advantages, but some concerns remain regarding respiratory and/or cardiac …
Small patients, big challenges: navigating pediatric drug manipulations to prevent medication errors-a comprehensive review
K Chachlioutaki, C Gioumouxouzis… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Medication errors during drug manipulations in pediatric care pose significant
challenges to patient safety and optimal medication management. Epidemiological studies …
challenges to patient safety and optimal medication management. Epidemiological studies …
Gaps in accessibility of pediatric formulations: A cross-sectional observational study of a teaching hospital in northern Thailand
P Tiengkate, M Lallemant, P Charoenkwan… - Children, 2022 - mdpi.com
The lack of appropriate medicines for children has a significant impact on health care
practices in various countries around the world, including Thailand. The unavailability of …
practices in various countries around the world, including Thailand. The unavailability of …
Relationship between adverse drug reactions and unlicensed/off-label drug use in hospitalized children (EREMI): A study protocol
KA Nguyen, Y Mimouni, E Jaberi, N Paret, I Boussaha… - Therapies, 2021 - Elsevier
Introduction To date, few studies have shown a significant association between off-label
drug use and adverse drug reactions (ADRs). The main aims of this study is to evaluate the …
drug use and adverse drug reactions (ADRs). The main aims of this study is to evaluate the …
Understanding pediatric drug lag time: Review of selected drug package inserts
A Beleck, S Nachman - Journal of the Pediatric Infectious …, 2021 - academic.oup.com
The wait for a pharmaceutical drug to become approved by the FDA for pediatrics lasts
approximately 8 years longer than that for adults. One of the reasons given is the concern …
approximately 8 years longer than that for adults. One of the reasons given is the concern …
[HTML][HTML] Use of off-label medications in a neonatal intensive care unit
EIA Koszma, AJB Bispo, IAO Santana… - Revista Paulista de …, 2021 - SciELO Brasil
Objective: This paper aims to analyze the use of off label (OL) medicines, according to the
National Regulatory Agency, in a neonatal intensive care unit of a high-risk maternity …
National Regulatory Agency, in a neonatal intensive care unit of a high-risk maternity …