Extemporaneous preparations are still widely prescribed for pediatric patients with special
treatments of certain doses and/or combinations of drugs. Several problems related to …

Background Off-label and unlicensed prescriptions pose a severe safety concern among the
pediatric population. We aimed to summarize the up-to-date evidence on the extent …

There is a serious need of pediatric drug formulations, whose lack causes the frequent use
of extemporaneous preparations obtained from adult dosage forms, with consequent safety …

Background Off-label drug use embodies a thorough clinical diagnosis and evaluation of
treatment needs and should not be confused with unreasonable drug use, but it also faces …

Propofol is one of the most widely used drugs for paediatric procedural sedation owing to its
known advantages, but some concerns remain regarding respiratory and/or cardiac …

Introduction Medication errors during drug manipulations in pediatric care pose significant
challenges to patient safety and optimal medication management. Epidemiological studies …

The lack of appropriate medicines for children has a significant impact on health care
practices in various countries around the world, including Thailand. The unavailability of …

Introduction To date, few studies have shown a significant association between off-label
drug use and adverse drug reactions (ADRs). The main aims of this study is to evaluate the …

The wait for a pharmaceutical drug to become approved by the FDA for pediatrics lasts
approximately 8 years longer than that for adults. One of the reasons given is the concern …

Objective: This paper aims to analyze the use of off label (OL) medicines, according to the
National Regulatory Agency, in a neonatal intensive care unit of a high-risk maternity …