Chronic kidney disease (CKD) is an increasing global health burden. Current treatments for
CKD include therapeutics to target factors that contribute to CKD progression, including …

The human microbiome has been proven to contribute to the human condition, both in
health and in disease. The metagenomic approach based on next-generation sequencing …

The amount of biological sequencing data available in public repositories is growing
exponentially, forming an invaluable biomedical research resource. Yet, making all this …

Background Haematological patients exhibit immune system abnormalities that make them
susceptible to viral infections. Understanding the relationship between the virome in the …

Viral infections are the leading cause of childhood acute febrile illnesses motivating
consultation in sub-Saharan Africa. The majority of causal viruses are never identified in low …

Introduction Immunosuppression after kidney transplantation (KTx) exposes recipients to
Human Polyomaviruses (HPyVs) infections, whose natural history is still misunderstood …

Generative probabilistic modeling of biological sequences has widespread existing and
potential use across biology and biomedicine, particularly given advances in high …

Abstract Introduction Human polyomaviruses (HPyVs) cause disease in
immunocompromised patients. BK polyomavirus (BKPyV) for instance persistently infects the …

Background Metagenomic next-generation sequencing (mNGS) has emerged as an
effective method for the noninvasive and precise detection of infectious pathogens …

Postoperative JC viruria is common in kidney transplant recipients, however there remains a
dearth of research on perioperative JCV infection in this population. The clinical significance …