MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …

ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …

Cytokines are important mediators of various aspects of health and disease, including
appetite, glucose and lipid metabolism, insulin sensitivity, skeletal muscle hypertrophy and …

Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …

Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides
TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes …

Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …

The tumor suppressor PDCD4 is a proinflammatory protein that promotes activation of the
transcription factor NF-κB and suppresses interleukin 10 (IL-10). Here we found that mice …

Toll-like receptor (TLR) signalling must be tightly regulated to avoid excessive inflammation
and to allow for tissue repair and the return to homeostasis after infection and tissue injury …

Neuroimmune diseases have diverse symptoms and etiologies but all involve pathological
inflammation that affects normal central nervous system signaling. Critically, many …