In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates

BAD Neto, PS Beck, JEP Sorto, MN Eberlin - Molecules, 2022 - mdpi.com
We discuss herein the problems associated with using melting points to characterize
multicomponent reactions'(MCRs) products and intermediates. Although surprising, it is not …

Design and synthesis of novel quinazolinone–chalcone hybrids as potential apoptotic candidates targeting caspase-3 and PARP-1: in vitro, molecular docking, and …

EA Madbouly, ESM Lashine, AA Al-Karmalawy… - New Journal of …, 2022 - pubs.rsc.org
A new series of thirty-one quinazolinone–chalcone hybrid molecules 13–43 were designed,
synthesized, and structurally characterized by different spectroscopic techniques. All the …

Parasitic diarrheal disease: drug development and targets

A Azam, MN Peerzada, K Ahmad - Frontiers in microbiology, 2015 - frontiersin.org
Diarrhea is the manifestation of gastrointestinal infection and is one of the major causes of
mortality and morbidity specifically among the children of less than 5 years age worldwide …

Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1, 2, 3] triazoles

KD Khalil, SM Riyadh, SM Gomha, I Ali - International journal of biological …, 2019 - Elsevier
Chitosan copper (II) oxide nanocomposite was synthesized, characterized and used to
synthesize [1, 2, 3] triazoles. Nanocomposite was characterized by using FTIR, XRD …

Antimicrobial activity of xanthohumol and its selected structural analogues

M Stompor, B Żarowska - Molecules, 2016 - mdpi.com
The objective of this study was to evaluate the antimicrobial activity of structural analogues
of xanthohumol 1, a flavonoid compound found in hops (Humulus lupulus). The agar …

Carbonylative Heck Reactions Using CO Generated ex Situ in a Two-Chamber System

P Hermange, TM Gøgsig, AT Lindhardt… - Organic …, 2011 - ACS Publications
A carbonylative Heck reaction of aryl iodides and styrene derivatives employing a two-
chamber system using a stable, crystalline, and nontransition metal based carbon monoxide …

Antimycobacterial and anti-inflammatory activities of substituted chalcones focusing on an anti-tuberculosis dual treatment approach

TLB Ventura, SD Calixto, BA Abrahim-Vieira… - Molecules, 2015 - mdpi.com
Tuberculosis (TB) remains a serious public health problem aggravated by the emergence of
M. tuberculosis (Mtb) strains resistant to multiple drugs (MDR). Delay in TB treatment …

Microwave assisted solvent free synthesis of 1, 3-diphenylpropenones

D Kakati, JC Sarma - Chemistry central journal, 2011 - Springer
Abstract Background 1, 3-Diphenylpropenones (chalcones) are well known for their diverse
array of bioactivities. Hydroxyl group substituted chalcones are the main precursor in the …

[HTML][HTML] Synthesis, biological evaluation, and molecular docking studies of resveratrol derivatives possessing chalcone moiety as potential antitubulin agents

BF Ruan, X Lu, JF Tang, Y Wei, XL Wang… - Bioorganic & medicinal …, 2011 - Elsevier
Twenty-three resveratrol derivatives possessing chalcone moiety were synthesized and
characterized, and their biological activities were also evaluated as potential …

Synthesis of leading chalcones with high antiparasitic, against Hymenolepis nana, and antioxidant activities

JT Díaz-Carrillo, SP Díaz-Camacho… - Brazilian Journal of …, 2018 - SciELO Brasil
The hymenolepiosis by Hymenolepis nana is a major public health problem in developing
countries, and the commercial drugs against this parasitosis are not enough effective. The …