Pharmacokinetics and pharmacodynamics of cyclodextrin-based oral drug delivery formulations for disease therapy

H Liu, S Guo, S Wei, J Liu, B Tian - Carbohydrate Polymers, 2024 - Elsevier
Oral drug administration has become the most common and preferred mode of disease
treatment due to its good medication adherence and convenience. For orally administered …

[HTML][HTML] Short review on the biological activity of cyclodextrin-drug inclusion complexes applicable in veterinary therapy

M Grecu, B Minea, LG Foia, AC Bostanaru-Iliescu… - Molecules, 2023 - mdpi.com
Cyclodextrins (CDs) are a family of carrier molecules used to improve the pharmacokinetic
parameters of therapeutic molecules. These cyclic oligosaccharides have medical and …

[HTML][HTML] Sponge-like macroporous cyclodextrin-based cryogels for controlled drug delivery

C Zagni, A Coco, T Mecca, G Curcuruto… - Materials Chemistry …, 2023 - pubs.rsc.org
New drug delivery systems for wound healing applications based on α/β/γ-cyclodextrin
(α/β/γ-CD) acrylic (A) and styrenic (S) monomers have been synthesized and co …

A honokiol-mediated robust coating for blood-contacting devices with anti-inflammatory, antibacterial and antithrombotic properties

L Li, C Chen, C Zhang, R Luo, X Lan, F Guo… - Journal of Materials …, 2021 - pubs.rsc.org
Thrombus, bacterial infections, and severe inflammation are still serious problems that have
to be faced with blood-contacting materials. However, it is a great challenge to …

Thrombotic microenvironment responsive crosslinking cyclodextrin metal-organic framework nanocarriers for precise targeting and thrombolysis

C Yuan, Y Ye, E Hu, R Xie, B Lu, K Yu, W Ding… - Carbohydrate …, 2024 - Elsevier
Global public health is seriously threatened by thrombotic disorders because of their high
rates of mortality and disability. Most thrombolytic agents, especially protein-based …

Transdermal delivery of inflammatory factors regulated drugs for rheumatoid arthritis

Y Zhang, Z Gao, S Chao, W Lu, P Zhang - Drug Delivery, 2022 - Taylor & Francis
Rheumatoid arthritis is a chronic autoimmune disease, with the features of recurrent chronic
inflammation of synovial tissue, destruction of cartilage, and bone erosion, which further …

Electrospun hydroxypropyl-β-cyclodextrin nanofibers loaded with anti-inflammatory drugs for potential therapeutic wound dressings

V Meenatchi, A Sood, R Bhaskar, SS Han - Journal of Molecular Liquids, 2024 - Elsevier
Electrospun cyclodextrin nanofibers as innovative drug delivery structures offer efficient,
selective, and controlled drug release. In the present work, free-standing nanofibrous webs …

[HTML][HTML] Cyclodextrins as anti-inflammatory agents: basis, drugs and perspectives

SL Appleton, S Navarro-Orcajada… - …, 2021 - ncbi.nlm.nih.gov
Inflammation is a biological response of the immune system to harmful stimuli. Importantly,
inflammation is also a hallmark of several human diseases such as cancer or diabetes …

[HTML][HTML] Cyclodextrins as anti-inflammatory agents: basis, drugs and perspectives

S Lucia Appleton, S Navarro-Orcajada… - Biomolecules, 2021 - mdpi.com
Inflammation is a biological response of the immune system to harmful stimuli. Importantly,
inflammation is also a hallmark of several human diseases such as cancer or diabetes …

[HTML][HTML] Development of innovative electrospun nepafenac-loaded nanofibers-based ophthalmic inserts

S Omer, N Nagy, E Szőcs, S Kádár, G Völgyi… - International Journal of …, 2023 - Elsevier
Electrospun nanofibers can be utilized to develop patient-centric ophthalmic formulations
with reasonable bioavailability at the targeted site. The current study aimed to develop 0.1 …