Alagille syndrome (ALGS) is an autosomal dominant, multisystem disorder with variable
phenotypic penetrance that was first described in 1969 by Daniel Alagille. Initial diagnosis …

Liver biopsy (LB) is still the criterion standard procedure for obtaining liver tissue for
histopathological examination and a valuable tool in the diagnosis, prognosis, and …

Methods: Electronic databases and proceedings from key congresses were searched in
accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses …

Alagille syndrome (ALGS) is an autosomal dominant disorder caused by pathogenic
variants in JAG1 or NOTCH2, which encode fundamental components of the Notch signaling …

Alagille syndrome is an autosomal dominant, complex multisystem disorder characterized
by the presence of three out of five major clinical criteria: cholestasis with bile duct paucity …

Alagille syndrome (ALGS) is a multisystem disease characterized by cholestasis and bile
duct paucity on liver biopsy in addition to variable involvement of the heart, eyes, skeleton …

Alagille syndrome (ALGS) is an autosomal dominant multisystem disorder with cholestasis
as a defining clinical feature. We sought to characterize hepatic outcomes in a molecularly …

Despite the robust healing capacity of the liver, regenerative failure underlies numerous
hepatic diseases, including the JAG1 haploinsufficient disorder, Alagille syndrome (ALGS) …

Alagille syndrome (ALGS) is a multisystem disorder that manifests as childhood cholestasis.
Reports of liver transplantation (LT) for patients with ALGS have come largely from single …

Alagille syndrome (ALGS) is the most common inherited cholestatic liver disease
encountered by pediatric hepatologists. Unlike most other causes of cholestasis, the …