Langerhans cell histiocytosis in children: history, classification, pathobiology, clinical manifestations, and prognosis

J Krooks, M Minkov, AG Weatherall - Journal of the American Academy of …, 2018 - Elsevier
Langerhans cell histiocytosis (LCH) is an inflammatory neoplasia of myeloid precursor cells
driven by mutations in the mitogen-activated protein kinase pathway. When disease involves …

Langerhans cell histiocytosis in children–a disease with many faces. Recent advances in pathogenesis, diagnostic examinations and treatment

M Jezierska, J Stefanowicz, G Romanowicz… - … in Dermatology and …, 2018 - termedia.pl
Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of
CD1a-positive immature dendritic cells. The purpose of this article was to present an …

Diverse cutaneous presentations of Langerhans cell histiocytosis in children: a retrospective cohort study

MA Morren, K Vanden Broecke… - Pediatric blood & …, 2016 - Wiley Online Library
Background Langerhans cell histiocytosis (LCH) is a rare disease, frequently affecting
young children. Procedure We performed a retrospective study in patients younger than 16 …

Gender aspects in skin diseases

W Chen, M Mempel, C Traidl‐Hofmann… - Journal of the …, 2010 - Wiley Online Library
Gender differences in medicine have been recognized in anatomy, physiology, as well as in
epidemiology and manifestations of various diseases. With respect to skin disorders, males …

Clinical features and treatment outcomes of Langerhans cell histiocytosis: a nationwide survey from Korea histiocytosis working party

BE Kim, KN Koh, JK Suh, HJ Im, JS Song… - Journal of Pediatric …, 2014 - journals.lww.com
A nationwide survey was conducted to clarify the clinical features and outcomes of Korean
children with Langerhans cell histiocytosis (LCH). Korea Histiocytosis Working Party …

Rare lung diseases III: Pulmonary Langerhans' cell histiocytosis

SC Juvet, D Hwang, GP Downey - Canadian Respiratory …, 2010 - Wiley Online Library
Pulmonary Langerhans' cell histiocytosis (PLCH) is an unusual cystic lung disease that is
also characterized by extrapulmonary manifestations. The current review discusses the …

Langerhans' cell histiocytosis of the liver in adults

M Abdallah, T Généreau, J Donadieu, JF Emile… - Clinics and research in …, 2011 - Elsevier
Among adults, liver involvement is relatively frequent in Langerhans' cell histiocytosis (LCH),
even though it is often overlooked. In fact, the liver involvement may be missed in apparently …

[HTML][HTML] Liver involvement of Langerhans' cell histiocytosis in children

X Yi, T Han, H Zai, X Long, X Wang… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Objective: Liver involvement is relatively frequent in children with Langerhans cell
histiocytosis (LCH). Its features remain poorly defined. Methods: A retrospective study was …

[HTML][HTML] The child with bone pain: malignancies and mimickers

MB McCarville - Cancer Imaging, 2009 - ncbi.nlm.nih.gov
Bone pain in children is common. The cause may be as benign as growing pains or as life-
threatening as a malignancy. When a cause cannot be established by laboratory tests …

Langerhans cell histiocytosis in children: a retrospective case series of 126 cases

S Dhar, SM Srinivas, S Dhar, S Basu… - Pediatric …, 2020 - Wiley Online Library
Abstract Background/Objectives Langerhans cell histiocytosis (LCH), a rare neoplasm of
hematopoietic myeloid precursor cells, is clinically characterized by spontaneously resolving …