Selenium biofortification: roles, mechanisms, responses and prospects

A Hossain, M Skalicky, M Brestic, S Maitra, S Sarkar… - Molecules, 2021 - mdpi.com
The trace element selenium (Se) is a crucial element for many living organisms, including
soil microorganisms, plants and animals, including humans. Generally, in Nature Se is taken …

Mitochondria as potential targets in Alzheimer disease therapy: an update

G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Zinc and selenium supplementation in COVID-19 prevention and treatment: a systematic review of the experimental studies

E Balboni, F Zagnoli, T Filippini… - Journal of Trace …, 2022 - Elsevier
Background and aim The COVID-19 pandemic has severely affected the world's population
in the last two years. Along with non-pharmacological public health interventions, major …

Association of antioxidant supplement use and dementia in the prevention of Alzheimer's disease by vitamin E and selenium trial (PREADViSE)

RJ Kryscio, EL Abner, A Caban-Holt, M Lovell… - JAMA …, 2017 - jamanetwork.com
Importance Oxidative stress is an established dementia pathway, but it is unknown if the use
of antioxidant supplements can prevent dementia. Objective To determine if antioxidant …

Environmental selenium and human health: an update

M Vinceti, T Filippini, LA Wise - Current environmental health reports, 2018 - Springer
Abstract Purpose of Review Selenium, a trace element, is ubiquitous in the environment.
The main source of human exposure is diet. Despite its nutritional benefits, it is one of the …

Selenium for preventing cancer

M Vinceti, T Filippini, C Del Giovane… - Cochrane database …, 2018 - cochranelibrary.com
Background This review is the third update of the Cochrane review" Selenium for preventing
cancer". Selenium is a naturally occurring element with both nutritional and toxicological …

Importance of selenium and selenoprotein for brain function: From antioxidant protection to neuronal signalling

ND Solovyev - Journal of inorganic biochemistry, 2015 - Elsevier
Multiple biological functions of selenium manifest themselves mainly via 25 selenoproteins
that have selenocysteine at their active centre. Selenium is vital for the brain and seems to …

Scientific opinion on the tolerable upper intake level for selenium

EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2023 - Wiley Online Library
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel
Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the tolerable …

Multilevel impacts of iron in the brain: the cross talk between neurophysiological mechanisms, cognition, and social behavior

A Ferreira, P Neves, R Gozzelino - Pharmaceuticals, 2019 - mdpi.com
Iron is a critical element for most organisms, which plays a fundamental role in the great
majority of physiological processes. So much so, that disruption of iron homeostasis has …

Selenium nanoparticles as an efficient nanomedicine for the therapy of Huntington's disease

W Cong, R Bai, YF Li, L Wang… - ACS applied materials & …, 2019 - ACS Publications
Huntington's disease (HD) is an incurable disease with progressive loss of neural function,
which is influenced by epigenetic, oxidative stress, metabolic, and nutritional factors …