[HTML][HTML] Unveiling the angiogenic effects of cannabinoids: enhancers or inhibitors?
J Maia, BM Fonseca, N Teixeira… - Biochemical …, 2023 - Elsevier
Cannabinoids are compounds found in the cannabis sativa plant. Cannabinoids, such as
delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), have potential therapeutic …
delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), have potential therapeutic …
Exosomal delivery of cannabinoids against cancer
Exosomes are extracellular vesicles (EVs) originating from endosomes that play a role in
cellular communication. These vesicles which mimic the parental cells that release them are …
cellular communication. These vesicles which mimic the parental cells that release them are …
Targeting Nrf2 signaling pathway in cancer prevention and treatment: the role of cannabis compounds
A Rybarczyk, A Majchrzak-Celińska, V Krajka-Kuźniak - Antioxidants, 2023 - mdpi.com
The development and progression of cancer are associated with the dysregulation of
multiple pathways involved in cell proliferation and survival, as well as dysfunction in redox …
multiple pathways involved in cell proliferation and survival, as well as dysfunction in redox …
Hypericum roeperianum bark extract suppresses breast cancer proliferation via induction of apoptosis, downregulation of PI3K/Akt/mTOR signaling cascade and …
MGF Guefack, D Talukdar, R Mukherjee, S Guha… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Hypericum roeperianum is a medicinal spice traditionally
used in West Africa to treat female sterility, fungal infections, and cancer. It has previously …
used in West Africa to treat female sterility, fungal infections, and cancer. It has previously …
Cannabidiol and beta-caryophyllene combination attenuates diabetic neuropathy by inhibiting NLRP3 inflammasome/NFκB through the AMPK/sirT3/nrf2 axis
Background: In this study, we investigated in detail the role of cannabidiol (CBD), beta-
caryophyllene (BC), or their combinations in diabetic peripheral neuropathy (DN). The key …
caryophyllene (BC), or their combinations in diabetic peripheral neuropathy (DN). The key …
Enhanced oral bioavailability and in vitro evaluation of cannabidiol camel milk-derived exosome formulation in resistant MDA-MB-231 and MDA-MB-468 breast …
The potential of camel milk-derived exosomes (CMDE) to enhance the bioavailability of
Cannabidiol (CBD) was investigated. CBD-CMDE formulation was prepared using an …
Cannabidiol (CBD) was investigated. CBD-CMDE formulation was prepared using an …
[HTML][HTML] Unlocking the Potential of Camel Milk-Derived Exosomes as Novel Delivery Systems: Enhanced Bioavailability of ARV-825 PROTAC for Cancer Therapy
This study investigates the use of camel milk-derived exosomes (CMEs) as carriers for ARV-
825, an anticancer agent targeting bromodomain-containing protein 4 (BRD4), in oral …
825, an anticancer agent targeting bromodomain-containing protein 4 (BRD4), in oral …
Combined Role of Interleukin-15 Stimulated Natural Killer Cell-Derived Extracellular Vesicles and Carboplatin in Osimertinib-Resistant H1975 Lung Cancer Cells with …
In this study, we evaluated IL-15 stimulated natural killer cell-derived EVs (NK-EVs) as
therapeutic agents in vitro and in vivo in Osimertinib-resistant lung cancer (H1975R) with …
therapeutic agents in vitro and in vivo in Osimertinib-resistant lung cancer (H1975R) with …
[PDF][PDF] Identification of Genes Hub Associated with Triple-Negative Breast Cancer and Cannabidiol Analogs Potential Inhibitory Agents: An In-silico Study
N Contreras-Puentes, A Alviz-Amador… - Asian Pacific Journal …, 2024 - researchgate.net
Objective: Triple-negative breast cancer presents a significant challenge in oncology due to
its complex treatment and aggressive nature. This subtype lacks common cancer cell …
its complex treatment and aggressive nature. This subtype lacks common cancer cell …