Tumour budding in solid cancers
Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other
solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of …
solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of …
The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives
J Majidpoor, K Mortezaee - Clinical Immunology, 2021 - Elsevier
Colorectal cancer (CRC), and breast, ovarian, pancreatic and prostate cancers are generally
considered as low immune-reactive cancers that represent either limited infiltration of …
considered as low immune-reactive cancers that represent either limited infiltration of …
Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response
Y Wang, Y Liang, H Xu, X Zhang, T Mao, J Cui, J Yao… - Cell discovery, 2021 - nature.com
The current pathological and molecular classification of pancreatic ductal adenocarcinoma
(PDAC) provides limited guidance for treatment options, especially for immunotherapy …
(PDAC) provides limited guidance for treatment options, especially for immunotherapy …
Composition, spatial characteristics, and prognostic significance of myeloid cell infiltration in pancreatic cancer
SA Väyrynen, J Zhang, C Yuan, JP Väyrynen… - Clinical Cancer …, 2021 - AACR
Purpose: Although abundant myeloid cell populations in the pancreatic ductal
adenocarcinoma (PDAC) microenvironment have been postulated to suppress antitumor …
adenocarcinoma (PDAC) microenvironment have been postulated to suppress antitumor …
The immune landscape of human pancreatic ductal carcinoma: key players, clinical implications, and challenges
M Muller, V Haghnejad, M Schaefer, G Gauchotte… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive
and deadliest cancer worldwide, with an overall survival (OS) rate, all stages combined, of …
and deadliest cancer worldwide, with an overall survival (OS) rate, all stages combined, of …
Current limitations and novel perspectives in pancreatic cancer treatment
S Robatel, M Schenk - Cancers, 2022 - mdpi.com
Simple Summary This review article presents a synopsis of the key clinical developments,
their limitations, and future perspectives in the treatment of pancreatic cancer. In the first part …
their limitations, and future perspectives in the treatment of pancreatic cancer. In the first part …
Electroporation and immunotherapy—unleashing the abscopal effect
Simple Summary Electrochemotherapy and irreversible electroporation are primarily used
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …
Tumor immune microenvironment-based therapies in pancreatic ductal adenocarcinoma: time to update the concept
W Luo, T Wen, X Qu - Journal of Experimental & Clinical Cancer Research, 2024 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor
immune microenvironment (TIME) formed by interactions among cancer cells, immune cells …
immune microenvironment (TIME) formed by interactions among cancer cells, immune cells …
Evaluation of tumour infiltrating lymphocytes in luminal breast cancer using artificial intelligence
Abstract Background Tumour infiltrating lymphocytes (TILs) are a prognostic parameter in
triple-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer …
triple-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer …
Correlation between lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and tumor-infiltrating lymphocytes …
C Gawiński, W Michalski, A Mróz, L Wyrwicz - Biology, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most common cancers worldwide.
Novel markers have been investigated in order to better predict the course of disease and …
Novel markers have been investigated in order to better predict the course of disease and …