Research Review: A guide to computing and implementing polygenic scores in developmental research

AG Allegrini, JR Baldwin, W Barkhuizen… - Journal of Child …, 2022 - Wiley Online Library
The increasing availability of genotype data in longitudinal population‐and family‐based
samples provides opportunities for using polygenic scores (PGS) to study developmental …

Myopia: is the nature‐nurture debate finally over?

IG Morgan, KA Rose - Clinical and Experimental Optometry, 2019 - Taylor & Francis
In the nineteenth century, the prevalence of myopia began to rise, and Cohn stressed the
role of education. Later, based on twin studies, Sorsby argued that refraction was almost …

The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence

AG Allegrini, R Cheesman, K Rimfeld… - Journal of child …, 2020 - Wiley Online Library
Background Diverse behaviour problems in childhood correlate phenotypically, suggesting
a general dimension of psychopathology that has been called the p factor. The shared …

A genetically informed Registered Report on adverse childhood experiences and mental health

JR Baldwin, HM Sallis, T Schoeler, MJ Taylor… - Nature human …, 2023 - nature.com
Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

A meta-analysis of genetic effects associated with neurodevelopmental disorders and co-occurring conditions

A Gidziela, YI Ahmadzadeh, G Michelini… - Nature human …, 2023 - nature.com
A systematic understanding of the aetiology of neurodevelopmental disorders (NDDs) and
their co-occurrence with other conditions during childhood and adolescence remains …

On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families

EM Eilertsen, R Cheesman, Z Ayorech… - Journal of child …, 2022 - Wiley Online Library
Background Theoretical models of the development of childhood externalizing disorders
emphasize the role of parents. Empirical studies have not been able to identify specific …

The genetic underpinnings of callous-unemotional traits: A systematic research review

AA Moore, RJ Blair, JM Hettema… - … & Biobehavioral Reviews, 2019 - Elsevier
Background Callous-unemotional (CU) traits represent the affective features of psychopathy
used to delineate youth at high risk for externalizing pathology. The genetic etiology CU …

[HTML][HTML] Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms

ES Jami, AR Hammerschlag, HF Ip, AG Allegrini… - Journal of the American …, 2022 - Elsevier
Objective To investigate the genetic architecture of internalizing symptoms in childhood and
adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies …

The molecular genetics of hand preference revisited

CGF De Kovel, C Francks - Scientific reports, 2019 - nature.com
Hand preference is a prominent behavioural trait linked to human brain asymmetry. A
handful of genetic variants have been reported to associate with hand preference or …

[HTML][HTML] Intracellular calcium dysregulation in autism spectrum disorder: an analysis of converging organelle signaling pathways

RL Nguyen, YV Medvedeva, TE Ayyagari… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a group of complex, neurological disorders that affect
early cognitive, social, and verbal development. Our understanding of ASD has vastly …