Zinc as a gatekeeper of immune function

I Wessels, M Maywald, L Rink - Nutrients, 2017 - mdpi.com
After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

[HTML][HTML] Cuproptosis and cuproptosis–related genes in rheumatoid arthritis: Implication, prospects, and perspectives

J Zhao, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease that severely affects patients' physical
and mental health, leading to chronic synovitis and destruction of bone joints. Although …

Zinc signals and immunity

M Maywald, I Wessels, L Rink - International journal of molecular sciences, 2017 - mdpi.com
Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …

The role of zinc and zinc homeostasis in macrophage function

H Gao, W Dai, L Zhao, J Min… - Journal of immunology …, 2018 - Wiley Online Library
Zinc has long been recognized as an essential trace element, playing roles in the growth
and development of all living organisms. In recent decades, zinc homeostasis was also …

Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases

M Suzuki, T Suzuki, M Watanabe… - Allergology …, 2021 - jstage.jst.go.jp
abstract Zinc is an essential micronutrient in human body and a vital cofactor for the function
of numerous proteins encoded by the human genome. Zinc has a critical role in maintaining …

Circulating level of blood iron and copper associated with inflammation and disease activity of rheumatoid arthritis

H Wang, R Zhang, J Shen, Y Jin, C Chang… - … Trace Element Research, 2023 - Springer
This study aims to compare the concentrations of circulating levels of iron, zinc, and copper
in blood samples of rheumatoid arthritis (RA) patients which determine the correlations with …

Zinc gluconate-loaded chitosan nanoparticles reduce severity of collagen-induced arthritis in Wistar rats

MM Ansari, A Ahmad, RK Mishra… - … Science & Engineering, 2019 - ACS Publications
Rheumatoid arthritis (RA) is the most prevalent autoimmune disease affecting about 1%
world population. Zinc (Zn) is necessary for the maintenance of bone homeostasis and the …

Study on sentinel symptoms and influencing factors of postoperative chemotherapy in patients with gastric cancer

L Wei, F Lv, C Luo, Y Fang - European Journal of Oncology Nursing, 2023 - Elsevier
Purpose To explore the symptom clusters of gastric cancer patients receiving postoperative
chemotherapy, identify the sentinel symptom of each symptom cluster, and compare the …

Expansion of rare and harmful lineages is associated with established rheumatoid arthritis

N Mena-Vázquez, P Ruiz-Limón… - Journal of Clinical …, 2020 - mdpi.com
Objectives: To characterize the gut microbiota profile in rheumatoid arthritis (RA) patients
and investigate its association with certain characteristics of RA. Patients and methods: A …

The association of trace elements with arthritis in US adults: NHANES 2013–2016

T Guan, Z Wu, C Xu, G Su - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
Background Arthritis is a common chronic disease, and is a major cause of disability and
chronic pain in adults. Considering inflammatory responses is closely related with trace …