Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Organs-on-a-chip (OOCs) are miniature tissues and organs grown in vitro that enable
modeling of human physiology and disease. The technology has emerged from converging …

Most cancer treatment strategies target cell proliferation, angiogenesis, migration, and
intravasation of tumor cells in an attempt to limit tumor growth and metastasis. An in vitro …

Urinary tract infections (UTIs) are among the most common infectious diseases worldwide
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive type of cancer with
an overall survival rate of less than 7-8%, emphasizing the need for novel effective …

Microfluidic organ-on-a-chip (Organ Chip) cell culture devices are often fabricated using
polydimethylsiloxane (PDMS) because it is biocompatible, transparent, elastomeric, and …

The role of skin in the human body is indispensable, serving as a barrier, moderating
homeostatic balance, and representing a pronounced endpoint for cosmetics and …

Membranes are fundamental elements within organ-on-a-chip (OOC) platforms, as they
provide adherent cells with support, allow nutrients (and other relevant molecules) to …

Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat
intracellular infections. They have outstanding performance in delivering antimicrobials …