Among different heterocyclic compounds, isoxazole and their analogues are very important
classes of heterocyclic compounds as they display an extensive range of biological actions …

A novel series of α-cyano indolylchalcones was prepared, and their chemical structures
were confirmed based on the different spectral data. Among them, compound 7f was …

A novel series of bis (furan‐based chalcone) derivatives linked to aliphatic linkers, with the
furan units at the A‐or B‐rings, were synthesized and evaluated as anticancer agents …

Abstract Ethyl 2‐acrylamido‐4, 5, 6, 7‐tetrahydrobenzo [b] thiophene‐3‐carboxylate as well
as its corresponding bis‐derivatives, 5–10, with aliphatic linkers were synthesized, fully …

Chalcones are interesting anticancer drug candidates which have attracted much interest
due to their unique structure and their extensive biological activity. Various functional …

We designed and prepared a novel series of urea derivatives with/without sulfonyl group in
their structures to investigate the impact of the sulfonyl group on the biological activity of the …

The reaction of an alkyl or aryl isocyanates with some primary amines in acetonitrile at room
temperature afforded the corresponding alkyl-and aryl-urea derivatives. All the prepared …

Background: Cancer is the second leading cause of death worldwide. Many anticancer
drugs are commercially available, but lack of selectivity, target specificity, cytotoxicity, and …

The drug resistance became the major challenge in the antimicrobial and anticancer drugs
therapy. Therefore, there is an urgent need to looking for new types of antimicrobial and …

Novel acylurea derivatives 7a–7ab were designed and synthesized by linking the active
substructures trifluoromethylpyridine and anthranilic diamide via an acylurea bridge. Most of …