Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

C Widmann, S Gibson, MB Jarpe… - Physiological …, 1999 - journals.physiology.org
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …

Signal transduction through MAP kinase cascades

TS Lewis, PS Shapiro, NG Ahn - Advances in cancer research, 1998 - Elsevier
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …

A comprehensive pathway map of epidermal growth factor receptor signaling

K Oda, Y Matsuoka, A Funahashi… - Molecular systems …, 2005 - embopress.org
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important
pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells …

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

AJ Whitmarsh, RJ Davis - Journal of molecular medicine, 1996 - Springer
Mitogen-activated protein (MAP) kinases are proline-directed serine/threonine kinases that
are activated by dual phosphorylation on threonine and tyrosine residues in response to a …

Pushing the limits of the scanning mechanism for initiation of translation

M Kozak - Gene, 2002 - Elsevier
Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a
scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in …

MAPK pathways in radiation responses

P Dent, A Yacoub, PB Fisher, MP Hagan, S Grant - Oncogene, 2003 - nature.com
Within the last 15 years, multiple new signal transduction pathways within cells have been
discovered. Many of these pathways belong to what is now termed 'the mitogen-activated …

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

B Xu, JM English, JL Wilsbacher, S Stippec… - Journal of Biological …, 2000 - ASBMB
We have cloned and characterized a novel mammalian serine/threonine protein kinase
WNK1 (withno lysine (K)) from a rat brain cDNA library. WNK1 has 2126 amino acids and …

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras

LB Rosen, DD Ginty, MJ Weber, ME Greenberg - Neuron, 1994 - cell.com
A pathway by which calcium influx through voltagesensitive calcium channels leads to
mitogen-activated protein kinase (MAPK) activation has been characterized. In PC12 cells …

Multiple myeloma: increasing evidence for a multistep transformation process

M Hallek, P Leif Bergsagel… - Blood, The Journal of …, 1998 - ashpublications.org
MULTIPLE MYELOMA (MM) is a clonal B-cell neo-plasm that affects terminally differentiated
B cells (ie, plasma cells) and may proceed through different phases: an inactive phase in …

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

CJ Marshall - Current opinion in genetics & development, 1994 - Elsevier
Signal transduction pathways that respond to external signals through the MAP kinase
family of protein kinases are involved in diverse responses in eukaryotic cells. MAP kinases …