Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …

Biological barriers hamper the efficient delivery of drugs and genes to targeted sites. Cell
penetrating peptides (CPP) have the ability to rapidly internalize across biological …

The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …

A major goal of synthetic biology is to understand the transition between non-living matter
and life. The bottom-up development of an artificial cell would provide a minimal system with …

Cell-penetrating peptides (CPPs) are naturally able to cross the lipid bilayer membrane that
protects cells. These peptides share common structural and physicochemical properties and …

The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …