Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling

X Zhou, VE Torres - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Autosomal dominant polycystic kidney disease (ADPKD), with an estimated genetic
prevalence between 1: 400 and 1: 1,000 individuals, is the third most common cause of end …

Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease

HJ Jung, EE Dixon, R Coleman… - Physiological …, 2023 - journals.physiology.org
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in
polycystin genes, Pkd1 and Pkd2, but the underlying pathogenic mechanisms are poorly …