The probabilistic gating of voltage-dependent ion channels is a source of electrical 'channel
noise'in neurons. This noise has long been implicated in limiting the reliability (repeatability) …

The highly interconnected local and large-scale networks of the neocortical sheet rapidly
and dynamically modulate their functional connectivity according to behavioral demands …

Cortical neurons exhibit tremendous variability in the number and temporal distribution of
spikes in their discharge patterns. Furthermore, this variability appears to be conserved over …

Predictive coding is a key mechanism to understand the computational processes
underlying brain functioning: in a hierarchical network, higher levels predict the activity of …

The classical view of neural coding has emphasized the importance of information carried
by the rate at which neurons discharge action potentials. More recent proposals that …

This study examines the ability of neurons to track temporally varying inputs, namely by
investigating how the instantaneous firing rate of a neuron is modulated by a noisy input with …

Temporal precision in spike timing is important in cortical function, interactions, and
plasticity. We found that, during periods of recurrent network activity (UP states), cortical …

Data from in vivo and in vitro experiments are discussed to emphasize that synaptic activities
in neocortex and thalamus have a decisive impact on intrinsic neuronal properties in intact …

Cortical neurons are sensitive to the timing of their synaptic inputs. They can synchronize
their firing on a millisecond time scale and follow rapid stimulus fluctuations with high …

The principle function of the central nervous system is to represent and transform information
and thereby mediate appropriate decisions and behaviors. The cerebral cortex is one of the …