Role of mitochondria in radiation responses: epigenetic, metabolic, and signaling impacts

D Averbeck, C Rodriguez-Lafrasse - International journal of molecular …, 2021 - mdpi.com
Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

Low-dose non-targeted effects and mitochondrial control

D Averbeck - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …

Advances in the current understanding of how low-dose radiation affects the cell cycle

MGM Khan, Y Wang - Cells, 2022 - mdpi.com
Cells exposed to ionizing radiation undergo a series of complex responses, including DNA
damage, reproductive cell death, and altered proliferation states, which are all linked to cell …

Control of neuroinflammation through radiation-induced microglial changes

A Boyd, S Byrne, RJ Middleton, RB Banati, GJ Liu - Cells, 2021 - mdpi.com
Microglia, the innate immune cells of the central nervous system, play a pivotal role in the
modulation of neuroinflammation. Neuroinflammation has been implicated in many diseases …

Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression

W Al-Khayyat, J Pirkkanen, J Dougherty, T Laframboise… - Cells, 2023 - mdpi.com
FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily.
FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in …

The scientific basis for the use of the linear no-threshold (LNT) model at low doses and dose rates in radiological protection

D Laurier, Y Billarand, D Klokov… - Journal of Radiological …, 2023 - iopscience.iop.org
The linear no-threshold (LNT) model was introduced into the radiological protection system
about 60 years ago, but this model and its use in radiation protection are still debated today …

[HTML][HTML] The LNT model for cancer induction is not supported by radiobiological data

BR Scott, S Tharmalingam - Chemico-biological interactions, 2019 - Elsevier
The hallmarks of cancer have been the focus of much research and have influenced the
development of risk models for radiation-induced cancer. However, natural defenses against …

Radiation in the atmosphere—A hazard to aviation safety?

MM Meier, K Copeland, KEJ Klöble, D Matthiä… - Atmosphere, 2020 - mdpi.com
Exposure of aircrew to cosmic radiation has been recognized as an occupational health risk
for several decades. Based on the recommendations by the International Commission on …

The response of living organisms to low radiation environment and its implications in radiation protection

M Belli, L Indovina - Frontiers in public health, 2020 - frontiersin.org
Life has evolved on Earth for about 4 billion years in the presence of the natural background
of ionizing radiation. It is extremely likely that it contributed, and still contributes, to shaping …

Effects of low dose ionizing radiation on the brain-a functional, cellular, and molecular perspective

RK Narasimhamurthy, KD Mumbrekar, BSS Rao - Toxicology, 2022 - Elsevier
Over the years, the advancement of radio diagnostic imaging tools and techniques has
radically improved the diagnosis of different pathophysiological conditions, accompanied by …