Background: Children have an augmented risk of pretreatment HIV drug resistance (PDR)
due to exposure to antiretroviral drugs for the prevention of mother-to-child transmission …

Abstract Purpose of Review With the expanded roll-out of antiretrovirals for treatment and
prevention of HIV during the last decade, the emergence of HIV drug resistance (HIVDR) …

Background: Over 90% of Human Immunodeficiency Virus (HIV) infected individuals will be
on treatment by 2020under UNAIDS 90-90-90 global targets. Under World Health …

Abstract Background. The International Maternal Pediatric Adolescent AIDS Clinical Trials
Network (IMPAACT) P1060 study demonstrated short-term superiority of lopinavir/ritonavir …

Interventions to prevent mother-to-child HIV transmission have been extremely successful,
but new HIV infections continue to occur in infants. Strong evidence indicates that …

Background Pretreatment HIV drug resistance (PDR) can impair virological response to
ART, jeopardizing effective treatment for children. Methods Children aged≤ 12 years …

Background Programs for the prevention of mother-to-child transmission (PMTCT) of human
immunodeficiency virus (HIV) have been scaled up in many low-and middle-income …

Introduction: The number of HIV‐infected children and adolescents requiring second‐line
antiretroviral treatment (ART) is increasing in low‐and middle‐income countries (LMIC) …

Introduction Pre‐treatment HIV drug resistance (PDR) is an increasing problem in sub‐
Saharan Africa. Children are an especially vulnerable population to develop PDR given that …

Objectives This manuscript describes the development, validation and clinical application of
a novel method for the quantification of the antiretroviral drug efavirenz in dried breast milk …