Mass-spectrometry-based proteomics, the large-scale analysis of proteins by mass
spectrometry, has emerged as a new technology over the last decade and become routine …

Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

The study of protein localisation has greatly benefited from high-throughput methods
utilising cellular fractionation and proteomic profiling. Hyperplexed Localisation of Organelle …

Centrosomes in animal cells are dynamic organelles with a proteinaceous matrix of
pericentriolar material assembled around a pair of centrioles. They organize the microtubule …

The proteome of the recently discovered bacterium Methylocella silvestris has been
characterized using three profiling and comparative proteomics approaches. The organism …

The organization of eukaryotic cells into distinct subcompartments is vital for all functional
processes, and aberrant protein localization is a hallmark of many diseases. Microscopy …

An increasing number of studies involve integrative analysis of gene and protein expression
data, taking advantage of new technologies such as next-generation transcriptome …

Within cells, proteins can co-assemble into functionally integrated and spatially restricted
multicomponent complexes. Often, the affinities between individual proteins are relatively …

The Golgi apparatus is the central organelle in the secretory pathway and plays key roles in
glycosylation, protein sorting, and secretion in plants. Enzymes involved in the biosynthesis …

This review provides an introduction for the nonspecialist to proteomics and in particular the
major approaches available for global protein identification and quantification. Proteomics …