Psychoactive drugs and male fertility: impacts and mechanisms

MA Hamed, VO Ekundina, RE Akhigbe - Reproductive Biology and …, 2023 - Springer
Although psychoactive drugs have their therapeutic values, they have been implicated in the
pathogenesis of male infertility. This study highlights psychoactive drugs reported to impair …

Agomelatine ameliorates cadmium-induced toxicity through the modification of HMGB-1/TLR-4/NFκB pathway

HM Hafez, S Waz, NFG El-Tahawy… - Toxicology and Applied …, 2022 - Elsevier
Cadmium (Cd) has potential hazards on human beings. Consequently, this study was
performed to explore the protective effects of agomelatine (AGO), a melatonin receptor …

Long‐Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats

A Matuszewska, B Nowak, W Niżański… - Oxidative Medicine …, 2021 - Wiley Online Library
Highly active antiretroviral therapy (HAART) is used in HIV‐infected patients. Alongside the
prolongation of patients' life, adverse side effects associated with long‐term therapy are …

Ketamine induced bladder fibrosis through MTDH/P38 MAPK/EMT pathway

Q Zhu, K Li, H Li, F Han, Z Tang, Z Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Purpose: Ketamine is an anesthetic in clinical, but it has also been used as an abusing drug
due to its low price and hallucinogenic effects. It is proved that ketamine abusing would …

Long-term effects of orchiopexy and orchiectomy on the testes of rats with testicular torsion

A Tasci, S Uguralp, AN Akatli, AK Arslan… - Journal of Pediatric …, 2022 - Elsevier
Introduction Ischemia/reperfusion injury occurs after testicular torsion, levels of free oxygen
radicals and inflammatory cytokines are increased in both the torsional and contralateral …

Role of EGF/ERK1/2/HO-1 axis in mediating methotrexate induced testicular damage in rats and the ameliorative effect of xanthine oxidase inhibitors

RR Rofaeil, MA Ibrahim, RH Mohyeldin… - …, 2023 - Taylor & Francis
Objectives: Methotrexate (MTX) is commonly used in the management of several
malignancies and autoimmune disorders; however, testicular damage is one of the most …

Repeated doses of ketamine affect the infant rat urogenital system

H Kasıkara, N Sungu, M Arslan, A Kucuk… - Drug design …, 2021 - Taylor & Francis
Aim Long-term ketamine use is known to create an interstitial cystitis-like problem in the
bladder. It is known that long-term intermittent ketamine is applied to the children receiving …

N-Methyl-d-aspartic Acid (NMDA) Receptor Is Involved in the Inhibitory Effect of Ketamine on Human Sperm Functions

Y Chen, W Xu, Y Yuan, H Chen, S Zheng, Y He… - International Journal of …, 2021 - mdpi.com
Ketamine, which used to be widely applied in human and animal medicine as a dissociative
anesthetic, has become a popular recreational drug because of its hallucinogenic effect. Our …

[PDF][PDF] Pooperacyjne zmiany endokrynologiczne u psów i kotów. Część II. Znieczulenie ogólne

O Gójska-Zygner, D Orzeł, K Jaworska - Życie Weterynaryjne, 2023 - bibliotekanauki.pl
Surgery in animals, like in humans, leads to endocrine changes. They result from both
surgical stress and drugs used in anaesthesiology. The authors of this review presented …