SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
FL Fontes-Dantas, GG Fernandes, EG Gutman… - Cell reports, 2023 - cell.com
Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
[HTML][HTML] Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study
N Owusu-Boaitey, TW Russell… - …, 2023 - eurosurveillance.org
Background Serological surveys have been the gold standard to estimate numbers of SARS-
CoV-2 infections, the dynamics of the epidemic, and disease severity. Serological assays …
CoV-2 infections, the dynamics of the epidemic, and disease severity. Serological assays …
High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 …
SMR Gomes, ACS Brito, WFP Manfro, M Ribeiro-Alves… - Plos one, 2023 - journals.plos.org
Background Cytokines induced by SARS-CoV-2 infection play a crucial role in the
pathophysiology of COVID-19 and hyperinflammatory responses have been associated with …
pathophysiology of COVID-19 and hyperinflammatory responses have been associated with …
SARS-CoV-2 Spike protein alters microglial purinergic signaling
VS Alves, SACS Santos, R Leite-Aguiar… - Frontiers in …, 2023 - frontiersin.org
Despite long-term sequelae of COVID-19 are emerging as a substantial public health
concern, the mechanism underlying these processes still unclear. Evidence demonstrates …
concern, the mechanism underlying these processes still unclear. Evidence demonstrates …
High mobility group box 1, ATP, lipid mediators, and tissue factor are elevated in COVID‐19 patients: HMGB1 as a biomarker of worst prognosis
ARR Vicentino, VS Fraga‐Junior… - Clinical and …, 2023 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2, the agent of the ongoing coronavirus
disease 2019 (COVID‐19) pandemic, has spread worldwide since it was first identified in …
disease 2019 (COVID‐19) pandemic, has spread worldwide since it was first identified in …
Intranasal liposomal formulation of spike protein adjuvanted with CpG protects and boosts heterologous immunity of hACE2 transgenic mice to SARS-CoV-2 infection
M Russo, MC Mendes-Corrêa, BB Lins, V Kersten… - Vaccines, 2023 - mdpi.com
Mucosal vaccination appears to be suitable to protect against SARS-CoV-2 infection. In this
study, we tested an intranasal mucosal vaccine candidate for COVID-19 that consisted of a …
study, we tested an intranasal mucosal vaccine candidate for COVID-19 that consisted of a …
Diminazene aceturate inhibits the SARS-CoV-2 spike protein-induced inflammation involving leukocyte migration and DNA extracellular traps formation
GC Pereira-Silva, CKCA Cornélio, G Pacheco… - Life Sciences, 2024 - Elsevier
Aims To investigate the SARS-CoV-2 Spike protein (Spk)-induced inflammatory response
and its downmodulation by diminazene aceturate (DIZE). Materials and methods Through …
and its downmodulation by diminazene aceturate (DIZE). Materials and methods Through …
Oligosymptomatic long-term carriers of SARS-CoV-2 display impaired innate resistance but increased high-affinity anti-spike antibodies
E Montes-Cobos, VC Bastos, C Monteiro… - Iscience, 2023 - cell.com
The vast spectrum of clinical features of COVID-19 keeps challenging scientists and
clinicians. Low resistance to infection might result in long-term viral persistence, but the …
clinicians. Low resistance to infection might result in long-term viral persistence, but the …
Genomic surveillance and serological profile of SARS-CoV-2 variants circulating in Macaé and nearby cities, southeastern Brazil
ACVF da Silva, CAO Silva, GF de Sousa… - Frontiers in …, 2024 - frontiersin.org
Introduction A characteristic of the COVID-19 pandemic has been the sequential emergence
and global dissemination of SARS-CoV-2 variants, noted for their enhanced transmission …
and global dissemination of SARS-CoV-2 variants, noted for their enhanced transmission …
High seroprevalence for SARS-CoV-2 infection in dogs: Age as risk factor for infection in shelter and foster home animals
MG Nilsson, MCS Cordeiro, ACA Gonçalves… - Preventive Veterinary …, 2024 - Elsevier
Abstract SARS-CoV-2 has caused 775 outbreaks in 29 animal species across 36 countries,
including dogs, cats, ferrets, minks, non-human primates, white-tailed deer, and lions …
including dogs, cats, ferrets, minks, non-human primates, white-tailed deer, and lions …