The ArcAB two-component system: function in metabolism, redox control, and infection

AN Brown, MT Anderson, MA Bachman… - Microbiology and …, 2022 - Am Soc Microbiol
ArcAB, also known as the Arc system, is a member of the two-component system family of
bacterial transcriptional regulators and is composed of sensor kinase ArcB and response …

New insights into transport capability of sugars and its impact on growth from novel mutants of Escherichia coli

A Alva, A Sabido-Ramos, A Escalante… - Applied microbiology and …, 2020 - Springer
The fast-growing capability of Escherichia coli strains used to produce industrially relevant
metabolites relies on their capability to transport efficiently glucose or potential industrial …

Optimizing E. coli as a formatotrophic platform for bioproduction via the reductive glycine pathway

S Kim, N Giraldo, V Rainaldi, F Machens… - … in Bioengineering and …, 2023 - frontiersin.org
Microbial C1 fixation has a vast potential to support a sustainable circular economy. Hence,
several biotechnologically important microorganisms have been recently engineered for …

Contextual flexibility in Pseudomonas aeruginosa central carbon metabolism during growth in single carbon sources

SK Dolan, M Kohlstedt, S Trigg, P Vallejo Ramirez… - MBio, 2020 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic human pathogen, particularly noted for
causing infections in the lungs of people with cystic fibrosis (CF). Previous studies have …

[HTML][HTML] A pulse of simulated root exudation alters the composition and temporal dynamics of microbial metabolites in its immediate vicinity

J Wiesenbauer, A König, S Gorka, L Marchand… - Soil Biology and …, 2024 - Elsevier
Root exudation increases the concentration of readily available carbon (C) compounds in its
immediate environment. This creates 'hotspots' of microbial activity characterized by …

Disrupting the ArcA regulatory network amplifies the fitness cost of tetracycline resistance in Escherichia coli

ML Arrieta-Ortiz, M Pan, A Kaur, E Pepper-Tunick… - Msystems, 2023 - Am Soc Microbiol
There is an urgent need for strategies to discover secondary drugs to prevent or disrupt
antimicrobial resistance (AMR), which is causing> 700,000 deaths annually. Here, we …

Sub-inhibitory antibiotic treatment selects for enhanced metabolic efficiency

SV Aduru, K Szenkiel, A Rahman, M Ahmad… - Microbiology …, 2024 - Am Soc Microbiol
Bacterial growth and metabolic rates are often closely related. However, under antibiotic
selection, a paradox in this relationship arises: antibiotic efficacy decreases when bacteria …

A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus

N Shahreen, J Ahn, A Alsiyabi, NB Chowdhury… - mSphere, 2024 - journals.asm.org
During aerobic growth, S. aureus relies on acetate overflow metabolism, a process where
glucose is incompletely oxidized to acetate, for its bioenergetic needs. Acetate is not …

[HTML][HTML] Role of substrate availability in the growth of Campylobacter co-cultured with extended spectrum beta-lactamase-producing Escherichia coli in Bolton broth

MI Lanzl, O Van Mastrigt, MH Zwietering, T Abee… - International Journal of …, 2022 - Elsevier
It is well-established that Extended-spectrum beta-lactamase-producing (ESBL-)
Escherichia coli challenge reliable detection of campylobacters during enrichment in Bolton …

Ivermectin Toxicokinetics in Rainbow Trout (Oncorhynchus mykiss) following P-glycoprotein Induction

VC Azevedo, CU Johnston… - Archives of …, 2024 - search.proquest.com
Abstract Alterations in ivermectin (IVM, 22, 23-dihydro avermectin B1a+ 22, 23-dihydro
avermectin B1b) toxicokinetics following P-glycoprotein (P-gp) induction by clotrimazole …