An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing
methods that contains continuously perfused chambers inhabited by living cells arranged to …

Microfluidic devices are finding increasing application as analytical systems, biomedical
devices, tools for chemistry and biochemistry, and systems for fundamental research …

Cell–material interactions constitute a key fundamental topic in biomaterials study. Various
cell cues and matrix cues as well as soluble factors regulate cell behaviors on materials …

This Account summarizes techniques for fabrication and applications in biomedicine of
microfluidic devices fabricated in poly (dimethylsiloxane)(PDMS). The methods and …

This review describes the pattering of proteins and cells using a non-photolithographic
microfabrication technology, which we callsoft lithography'because it consists of a set of …

We report on the surface modification of Sylgard-184 poly (dimethyl siloxane)(PDMS)
networks by ultraviolet (UV) radiation and ultraviolet/ozone (UVO) treatment. The effects of …

(57) ABSTRACT A microfluidic device for analyzing and/or sorting biological materials (eg,
molecules such as polynucleotides and polypeptides, including proteins and enzymes; …

The invention provides systems, including apparatus, methods, and kits, for the microfluidic
manipulation and/or detection of particles, such as cells and/or beads. The invention …

Three-dimensional microfluidic systems were fabricated and used to pattern proteins and
mammalian cells on a planar substrate. The three-dimensional topology of the microfluidic …

Recent progress in cell culture and microfabrication technologies has contributed to the
development of cell‐based biosensors for the functional characterization and detection of …