Respiratory syncytial virus entry and how to block it

MB Battles, JS McLellan - Nature Reviews Microbiology, 2019 - nature.com
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in
young children and elderly people. Although the virus was isolated in 1955, an effective …

Development of mRNA vaccines against respiratory syncytial virus (RSV)

X Qiu, S Xu, Y Lu, Z Luo, Y Yan, C Wang, J Ji - Cytokine & Growth Factor …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that is the
primary etiologic pathogen of bronchitis and pneumonia in infants and the elderly. Currently …

Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis

JL Nieto-Torres, ML DeDiego… - PLoS …, 2014 - journals.plos.org
Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E)
gene attenuates the virus. E gene encodes a small multifunctional protein that possesses …

Structure and function of respiratory syncytial virus surface glycoproteins

JS McLellan, WC Ray, ME Peeples - Challenges and opportunities for …, 2013 - Springer
The two major glycoproteins on the surface of the respiratory syncytial virus (RSV) virion, the
attachment glycoprotein (G) and the fusion glycoprotein (F), control the initial phases of …

Antibody effector functions are associated with protection from respiratory syncytial virus

YC Bartsch, D Cizmeci, J Kang, T Zohar, S Periasamy… - Cell, 2022 - cell.com
Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory tract
infection and death in young infants and the elderly. With no effective prophylactic treatment …

Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems

A García-Sastre, A Egorov, D Matassov, S Brandt… - Virology, 1998 - Elsevier
The NS1 protein is the only nonstructural protein encoded by influenza A virus. It has been
proposed that the NS1 performs several regulatory functions during the viral replication …

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years

PL Collins, JA Melero - Virus research, 2011 - Elsevier
Human respiratory syncytial virus (RSV) is a ubiquitous pathogen that infects everyone
worldwide early in life and is a leading cause of severe lower respiratory tract disease in the …

Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology

L Zhang, ME Peeples, RC Boucher, PL Collins… - Journal of …, 2002 - Am Soc Microbiol
Gene therapy for cystic fibrosis (CF) lung disease requires efficient gene transfer to airway
epithelial cells after intralumenal delivery. Most gene transfer vectors so far tested have not …

Viroporins and inflammasomes: a key to understand virus-induced inflammation

NS Farag, U Breitinger, HG Breitinger… - The international journal …, 2020 - Elsevier
Viroporins are virus encoded proteins that alter membrane permeability and can trigger
subsequent cellular signals. Oligomerization of viroporin subunits results in formation of a …

Bovine respiratory syncytial virus infection

JF Valarcher, G Taylor - Veterinary research, 2007 - hal.science
Bovine respiratory syncytial virus (BRSV) belongs to the pneumovirus genus within the
family Paramyxoviridae and is a major cause of respiratory disease in young calves. BRSV …