[HTML][HTML] Network-based approaches for modeling disease regulation and progression

G Galindez, S Sadegh, J Baumbach… - Computational and …, 2023 - Elsevier
Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …

SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype

D Bongiovanni, M Klug, O Lazareva, S Weidlich… - Cell death & …, 2021 - nature.com
Abstract Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable
state, characterized by abnormal coagulation parameters and by increased incidence of …

Target discovery for host-directed antiviral therapies: application of proteomics approaches

M Cakir, K Obernier, A Forget, NJ Krogan - Msystems, 2021 - Am Soc Microbiol
Current epidemics, such as AIDS or flu, and the emergence of new threatening pathogens,
such as the one causing the current coronavirus disease 2019 (COVID-19) pandemic …

An update on novel approaches for diagnosis and treatment of SARS-CoV-2 infection

A Safarchi, S Fatima, Z Ayati, F Vafaee - Cell & Bioscience, 2021 - Springer
The ongoing pandemic of coronavirus disease 2019 (COVID-19) has made a serious public
health and economic crisis worldwide which united global efforts to develop rapid, precise …

CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy

M Salgado-Albarrán, J Späth… - npj Systems Biology …, 2022 - nature.com
High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy
due to the lack of reliable biomarkers, effective treatment, and chemoresistance. Improving …

An update on betrixaban, the challenging anticoagulant agent for extended venous thromboembolism prophylaxis

Y Daryabari, F Amreek… - Journal of …, 2022 - journals.lww.com
Venous thromboembolism (VTE) is a prevalent yet preventable cause of death, particularly
among hospitalized patients. Studies have shown that the risk of VTE remains high for up to …

Drug Repurposing through Network Medicine

S Sadegh - 2024 - mediatum.ub.tum.de
The dissertation seeks to improve drug research efficiency through drug repurposing, the
exploration of new applications for existing drugs. The dissertation presents CoVex …

[PDF][PDF] Maestría y Doctorado en Ciencias Bioquímicas

PDELC COPI - 2020 - ru.dgb.unam.mx
Las gastroenteritis infecciosas agudas son la causa más frecuente de morbilidad y
mortalidad en niños menores de cinco años en los países en desarrollo. Un número …

[引用][C] Förderliche und hemmende Faktoren für die Implementierung der Systemmedizin im deutschen Gesundheitssystem

CM Lemmen - 2022 - Universität zu Köln