Three-component access to functionalized spiropyrrolidine heterocyclic scaffolds and their cholinesterase inhibitory activity

S Boudriga, S Haddad, V Murugaiyah, M Askri, M Knorr… - Molecules, 2020 - mdpi.com
A novel one-pot [3+ 2]-cycloaddition reaction of (E)-3-arylidene-1-phenyl-succinimides,
cyclic 1, 2-diketones (isatin, 5-chloro-isatin and acenaphtenequinone), and diverse α …

Activity against Mycobacterium tuberculosis of a new class of spirooxindolopyrrolidine embedded chromanone hybrid heterocycles

MF Alkaltham, AI Almansour, N Arumugam… - RSC …, 2024 - pubs.rsc.org
A new class of structurally intriguing heterocycles embedded with spiropyrrolidine, oxindole
and chromanones was prepared by regio-and stereoselectively in quantitative yields using …

Ru (ii)-Catalyzed spirocyclization of aryl N-sulfonyl ketimines with aryl isocyanates through an aromatic C–H bond activation

N ReddyáK - Organic & Biomolecular Chemistry, 2018 - pubs.rsc.org
A novel one-pot strategy has been developed for the construction of spiro-isoindolinone-
benzosultams through a Ru (II)-catalyzed sequential C–C and C–N bond formation. This …

Regioselective synthesis and biological evaluation of novel dispiropyrrolidine derivatives via one-pot four-component reaction

S Gopal Hegde, L Koodlur… - Synthetic …, 2019 - Taylor & Francis
A new series of regioselective dispiropyrrolidine analogs via efficient one-pot four-
component tandem reaction has been discovered. The reaction was carried out in the …

[PDF][PDF] Frontiers of Medicinal Chemistry

D Ding - academia.edu
Journal of Medicinal Chemistry deals with the study of pharmaceutical analysis and the
chemical analysis of compounds for the medicinal value. It also involves developing new …