As a critical component of the tumor microenvironment (TME), cancer‐associated fibroblasts
(CAFs) play important roles in cancer initiation and progression. Well‐known signaling …

Cancer cells are well-known for adapting their metabolism to maintain high proliferation
rates and survive in unfavorable environments with low oxygen and nutritional deficiency …

Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer
progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in …

Cancer is characterized by metabolic reprogramming, which is a hot topic in tumor treatment
research. Cancer cells alter metabolic pathways to promote their growth, and the common …

Glioblastoma is a primary malignant brain tumor with a median survival under 2 years. The
poor prognosis glioblastoma caries is largely due to cellular invasion, which enables escape …

It is notorious that cancer cells alter their metabolism to adjust to harsh environments of
hypoxia and nutritional starvation. Metabolic reprogramming most often occurs in the tumor …

The interplay between apoptotic cancer cells and the tumor microenvironment modulates
cancer progression and metastasis. Cancer-associated fibroblasts (CAFs) play a crucial role …

Simple Summary Breast cancer is the second leading cause of cancer-related death in
women in the United States. The Akt signaling pathway is deregulated in approximately 70 …

Metabolic reprogramming is a hallmark of human malignancies. Dysregulation of glutamine
metabolism is essential for tumorigenesis, microenvironment remodeling, and therapeutic …

Invasion and metastasis are the main reasons for the high mortality of liver cancer, which
involve the interaction of tumor stromal cells and malignant cells. Cancer-associated …